Previously seen journeys

Next departures from Florence to Chicago on 26 September
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	05:45	Florence, SC	1d 5h	09:50	Chicago 95Th & Dan Ryan
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	05:45	Florence, SC	1d 3h	08:15	Downtown Greyhound Station
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	05:45	Florence, SC	1d 3h	08:15	Downtown Greyhound Station
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	05:45	Florence, SC	1d 5h	09:50	Chicago 95Th & Dan Ryan
	Bus Wifi Toilet Power outlets	12:55	Bus station	1d 4h	15:55	Chicago 95Th & Dan Ryan

Compare 2 ways to travel from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 5 hours 5 minutes and with fares starting at just PLN 328, it presents an excellent value for a comfortable ride.

12bus per day

1d 5hAverage duration

1093 kmDistance

27kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average pricePLN 328 - PLN 2 141	Average duration1d 5h	CO₂ emissions 27kg CO₂e
Train	Average pricePLN 991 - PLN 6 890	Average duration1d 12h	CO₂ emissions 100kg CO₂e

Bus stations and stops in Florence and Chicago

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/588 170 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

WiFi2.5

FlixBus

3.5/515 882 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about travelling from Florence, SC, US to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Florence to Chicago?
The cheapest bus tickets from Florence to Chicago start at PLN 328. The average price for this route is around PLN 540. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Florence to Chicago?
The average bus journey time from Florence to Chicago is 1d 5h, covering a distance of 1093 km. The fastest bus gets you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Florence to Chicago route?
Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Florence to Chicago?
The earliest bus departs from Florence to Chicago at 00:05. And the latest bus departs at 19:20.
What are the CO₂ emissions for the bus trip from Florence to Chicago?
A bus trip from Florence to Chicago produces an estimated 27.311649999999997 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Florence to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88149 reviews.
Which bus company has the best Wi-Fi from Florence to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

23/09

PLN 354

24/09

PLN 437

Today

PLN 472

26/09

No data

27/09

No data

28/09

No data

29/09

PLN 411

30/09

No data

The cheapest trip from Florence, SC, US to Chicago was searched and found on 23 Sept 2026 with a price of PLN 354

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago as early as possible.

You can expect to pay from PLN 354 to PLN 516 for a bus ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 411, which is on 2026-09-29.