How much is the bus ticket from Florence to Chicago?

The cheapest bus tickets from Florence to Chicago start at R 2 118. The average price for this route is around R 3 193. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Florence to Chicago?

The average bus journey time from Florence to Chicago is 1d 3h, covering a distance of 1084 km. The fastest bus gets you there in 1d and is operated by Greyhound .

Which bus companies service the Florence to Chicago route?

Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Florence to Chicago?

The earliest bus departs from Florence to Chicago at 00:05. And the latest bus departs at 16:30.

What are the CO₂ emissions for the bus trip from Florence to Chicago?

A bus trip from Florence to Chicago produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Florence to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Florence to Chicago?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Florence to Chicago?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Florence to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Florence to Chicago from R 1 995 | Refundable Tickets

Next bus departures

Next departures from Florence to Chicago on 21 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	16:10	Bus station	1d	15:55	Chicago 95Th & Dan Ryan	Cheapest
	Bus	16:10	Bus station	1d	15:15	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	16:30	Bus station	1d 8h	00:10	Downtown Greyhound Station	No tags
	Bus	16:30	Bus station	1d 16h	08:00	537-517 W. Jackson Blvd	No tags
Greyhound Lines, Inc. + FlixBus	Bus	16:30	Bus station	1d 7h	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from Florence to Chicago on 22 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	05:45	Florence, SC	1d 5h	09:50	Chicago 95Th & Dan Ryan	Cheapest
	Bus	16:10	Bus station	1d	15:15	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55	Bus station	1d	11:30	Downtown Greyhound Station	No tags
	Bus	11:55	Bus station	1d 3h	14:10	537-517 W. Jackson Blvd	No tags
	Bus	00:05	Florence, SC	1d 6h	05:40	Chicago 95Th & Dan Ryan	No tags

Last refresh of the prices: Last Wednesday at 2:44 AM EST.

Compare 2 ways to travel from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 3 hours 30 minutes and with fares starting at just R 2 118, it presents an excellent value for a comfortable ride.

12bus per day

1d 3hAverage duration

1084 kmDistance

27kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 2 118 - R 10 081	Average duration1d 3h	CO₂ emissions 27kg CO₂e
Train	Average priceR 4 917 - R 32 738	Average duration1d 11h	CO₂ emissions 100kg CO₂e

Where are the popular stops in Florence and Chicago?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587 442 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511 677 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Florence, SC, US to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Florence to Chicago?
The cheapest bus tickets from Florence to Chicago start at R 2 118. The average price for this route is around R 3 193. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Florence to Chicago?
The average bus journey time from Florence to Chicago is 1d 3h, covering a distance of 1084 km. The fastest bus gets you there in 1d and is operated by Greyhound.
Which bus companies service the Florence to Chicago route?
Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Florence to Chicago?
The earliest bus departs from Florence to Chicago at 00:05. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from Florence to Chicago?
A bus trip from Florence to Chicago produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Florence to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Florence to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

19/12

R 2 520

20/12

R 3 483

Today

R 2 416

22/12

R 3 259

23/12

No data

24/12

No data

25/12

No data

26/12

No data

The cheapest trip from Florence, SC, US to Chicago was searched and found on 21 Dec 2025 with a price of R 2 416

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago as early as possible.

You can expect to pay from R 2 416 to R 7 120 for a bus ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 259, which is on 2025-12-22.