Bus Tickets from Florence, SC, US to Chicago

Find affordable bus tickets from Florence, SC, US to Chicago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 28
TomorrowJun 29
from US$177
MonJun 30
from US$124
TueJul 1
WedJul 2
ThuJul 3
FriJul 4
from US$127
SatJul 5

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 29 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 30 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 29 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 30 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 30 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 30 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: July 1 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 2:47 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Chicago

Bus
Average PriceUS$97 - US$392Average Duration1d 6h
27kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$284 - US$603Average Duration1d 11h
100kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Chicago

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 6 hours 41 minutes, and with fares starting at just US$97, it presents an excellent value for a comfortable ride.

9bus per day
1d 6hAverage Duration
US$97Cheapest ticket
27kgCO₂ emissions

Bus Florence to Chicago: Trip Overview

Average Ticket PriceUS$186
Average Bus Trip Duration1d 6h
Number of daily buses9
Earliest bus departure12:05am
Distance1097 km
Latest bus departure11:59pm

Florence to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Chicago.

We make sure you can find a bus service from Florence to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Florence to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence, SC, US - Chicago

  1. How far is Florence from Chicago?

    The distance between Florence and Chicago is around 1102 km (684 miles).

  2. What are the departure and arrival locations for buses traveling from Florence to Chicago?

    Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Downtown Greyhound Station, in Chicago.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Chicago.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Chicago

You can also go to Chicago by train

Train from Florence to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago