Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Pittsburgh Intermodal Station | CheapestFastest | ||||
 | Bus | 1116 Woodruff Rd | Pittsburgh Intermodal Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Pittsburgh Intermodal Station | No tags |
Last refresh of the prices: Today at 10:08 EST.
Compare 2 ways to travel from Greenville to Pittsburgh
Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 18 hours and with fares starting at just £86, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Pittsburgh?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
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Frequently asked questions about travelling by bus from Greenville, SC to Pittsburgh
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Greenville to Pittsburgh?
The cheapest coach tickets from Greenville to Pittsburgh start from £86. The average price for this route is around £116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Greenville to Pittsburgh?
The average bus journey time from Greenville to Pittsburgh is 18h, covering a distance of 408 miles. The fastest bus can take you there in 17h 5m and is operated by FlixBus.
Which bus companies service the Greenville to Pittsburgh route?
What is the earliest and latest departure time for the bus from Greenville to Pittsburgh?
The earliest bus departs from Greenville to Pittsburgh at 10:50. And the latest bus departs at 22:00.
What are the CO₂ emissions for the bus trip from Greenville to Pittsburgh?
A bus journey from Greenville to Pittsburgh produces an estimated 16 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Greenville to Pittsburgh?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which company has the best Wi-Fi from Greenville to Pittsburgh?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Greenville to Pittsburgh?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Pittsburgh?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Pittsburgh was searched and found on 14 Dec 2025 with a price of £82To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh as early as possible.
You can expect to pay from £82 to £110 for a bus ticket from Greenville, SC to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at £106, which is on 2025-12-15.
What's the cheapest way to go from Greenville, SC to Pittsburgh?
The bus is the cheapest travel choice for this destination
