Bus from Harrisburg to Chicago: Tickets & Timetables

Next bus departures

Next departures from Harrisburg to Chicago on 16 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Chicago 95Th & Dan RyanCheapest
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Downtown Greyhound StationFastest
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Downtown Greyhound StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Harrisburg Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc.Bus
Harrisburg Bus Station
Downtown Greyhound StationNo tags

Last refresh of the prices: Yesterday at 10:45 AM EST.

Compare 2 ways to travel from Harrisburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 18 hours 10 minutes and with fares starting at just R 1 362, it presents an excellent value for a comfortable ride.

9bus per day
18h 10mAverage duration
920 kmDistance
23kgCO₂ emissions
Average priceR 1 362 - R 6 471Average duration18h 10m
23kg CO₂e
Average priceR 1 766 - R 14 228Average duration20h 36m
84kg CO₂e

Frequently asked questions about travelling from Harrisburg to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Harrisburg to Chicago?

    The cheapest bus tickets from Harrisburg to Chicago start at R 1 362. The average price for this route is around R 2 360. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Harrisburg to Chicago?

    The average bus journey time from Harrisburg to Chicago is 18h 10m, covering a distance of 920 km. The fastest bus gets you there in 14h 45m and is operated by Greyhound.

  3. Which bus companies service the Harrisburg to Chicago route?

    Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Harrisburg to Chicago?

    The earliest bus departs from Harrisburg to Chicago at 02:30. And the latest bus departs at 21:10.

  5. What are the CO₂ emissions for the bus trip from Harrisburg to Chicago?

    A bus trip from Harrisburg to Chicago produces an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Harrisburg to Chicago?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.

  7. Which bus company has the best Wi-Fi from Harrisburg to Chicago?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Harrisburg to Chicago?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Harrisburg to Chicago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/12
R 1 961
14/12
R 4 352
Today
R 2 701
16/12
R 2 374
17/12
R 1 961
18/12
R 2 150
19/12
R 2 030
20/12
R 2 082
busbud logoThe cheapest trip from Harrisburg to Chicago was searched and found on 13 Dec 2025 with a price of R 1 961

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Chicago as early as possible.

You can expect to pay from R 1 961 to R 4 782 for a bus ticket from Harrisburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 961, which is on 2025-12-17.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Harrisburg to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

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