Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Transit Center | Des Moines | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Transit Center | Des Moines | Fastest | ||||
 | Bus | Indianapolis Bus Station | Des Moines | No tags |
Last refresh of the prices: Yesterday at 12:45 PM EST.
Get from Indianapolis to Des Moines
The journey takes about 15 hours 30 minutes, and with fares starting at just R 1 412, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Des Moines?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
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Frequently asked questions about travelling from Indianapolis to Des Moines by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Indianapolis to Des Moines?
The cheapest bus tickets from Indianapolis to Des Moines start at R 1 412. The average price for this route is around R 1 904. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Indianapolis to Des Moines?
The average bus journey time from Indianapolis to Des Moines is 15h 30m, covering a distance of 660 km. The fastest bus gets you there in 12h and is operated by Burlington Trailways.
Which bus companies service the Indianapolis to Des Moines route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Burlington Trailways, FlixBus.
What is the earliest and latest departure time for the bus from Indianapolis to Des Moines?
The earliest bus departs from Indianapolis to Des Moines at 00:05. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Indianapolis to Des Moines?
A bus trip from Indianapolis to Des Moines produces an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Indianapolis to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Des Moines?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company offers the most punctual service from Indianapolis to Des Moines?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Des Moines was searched and found on 17 Dec 2025 with a price of R 1 115To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines as early as possible.
You can expect to pay from R 1 115 to R 2 074 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 115, which is on 2025-12-17.
