Find coaches from Indianapolis to Des Moines

Next departures

Next departures from Indianapolis to Des Moines on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Des MoinesCheapest
Greyhound Lines, Inc.
Indianapolis Bus Station
Des MoinesFastest
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Des MoinesNo tags

Last refresh of the prices: Last Wednesday at 18:01 EDT.

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Bus Indianapolis to Des Moines: Trip Overview

Average ticket priceUS$95
Average bus trip duration16h 20m
Number of daily buses3
Earliest bus departure03:15
Distance410 miles
Latest bus departure21:35

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Des Moines

  1. What's the distance between Indianapolis and Des Moines by coach?

    The distance between Indianapolis and Des Moines by coach is approximately 410 miles (661 km).

  2. How can I travel from Indianapolis to Des Moines avoiding air travel?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/10
No data
09/10
US$91
Today
No data
11/10
No data
12/10
No data
13/10
US$67
14/10
No data
15/10
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on 13 Oct 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines as early as possible.

You can expect to pay from US$67 to US$113 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$67, which is on 2025-10-13.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Indianapolis to Des Moines will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Des Moines to Indianapolis

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