Bus Tickets from Indianapolis to Des Moines

Next departures

Next departures for Indianapolis to Des Moines on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Des MoinesCheapest
Greyhound Lines, Inc.
Indianapolis Bus Station
Des MoinesFastest
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Des MoinesNo tags

Last refresh of the prices: Yesterday at 6:01 PM EDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Indianapolis to Des Moines: Trip Overview

Average Ticket PriceUS$95
Average Bus Trip Duration16h 20m
Number of daily buses3
Earliest bus departure3:15am
Distance660 km
Latest bus departure9:35pm

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Des Moines

  1. How far is Indianapolis from Des Moines?

    The distance between Indianapolis and Des Moines is around 661 km (410 miles).

  2. What are the departure and arrival locations for buses traveling from Indianapolis to Des Moines?

    Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Jefferson/Trailways Depot, in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-07
US$84
10-08
No data
Today
US$91
10-10
No data
10-11
No data
10-12
No data
10-13
US$67
10-14
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on Oct 13, 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.

You can expect to pay from US$67 to US$113 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$67 which is on 2025-10-13.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Des Moines to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines