Bus Tickets from Indianapolis to Des Moines

Find affordable bus tickets from Indianapolis to Des Moines with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 16
from $77
TomorrowJul 17
FriJul 18
SatJul 19
SunJul 20
MonJul 21
TueJul 22
WedJul 23

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 16 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: July 17 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 16 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: July 17 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Indianapolis to Des Moines: Trip Overview

Average ticket price$97
Average bus trip duration18h
Number of daily buses2
Earliest bus departure7:10am
Distance410 miles (660 km)
Latest bus departure9:35pm

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Indianapolis - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/14
$89
07/15
$88
Today
$81
07/17
No data
07/18
No data
07/19
No data
07/20
No data
07/21
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on Jul 16, 2025 with a price of $81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Des Moines

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines