How much does a bus ticket from Lyon to Brussels cost?

The bus ticket price from Lyon to Brussels starts at US$26. The best way to find cheap bus tickets from Lyon to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Lyon to Brussels?

The average travel time between Lyon and Brussels is around 11h 50m, although the fastest bus will take about 8h 40m. This is the time it takes to travel the 569 km that separates the two cities.

How many daily bus connections are there between Lyon and Brussels?

The number of buses from Lyon to Brussels can differ depending on the day of the week. On average, there are 17 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Lyon to Brussels by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Lyon to Brussels?

When taking the bus from Lyon to Brussels, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.

What are the departure and arrival stations when taking the bus from Lyon to Brussels?

Buses travelling between Lyon and Brussels leave from Perrache or Lyon Airport and arrive at Brussels South (Gare du Midi), Brux-Nord, Congrès.

Bus Lyon to Brussels from US$26 | Refundable Tickets

Next departures

Next departures from Lyon to Brussels on 31 October
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
08:35	Lyon - Perrache Bus Station	11h 20m	19:55	Brussels North Train Station	Cheapest
20:40	Lyon - Perrache Bus Station	9h 40m	06:20	Brussels-South (Gare du Midi)	Fastest
05:00	Lyon - Perrache Bus Station	10h 15m	15:15	Brussels-South (Gare du Midi)	No tags
08:30	Aéroport LYS	18h 30m	03:00	Brussels North Train Station	No tags
06:20	Lyon - Perrache Bus Station	10h 10m	16:30	Brussels-South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 1 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
12:00	Lyon - Perrache Bus Station	11h 5m	23:05	Brussels-South (Gare du Midi)	Cheapest
20:40	Lyon - Perrache Bus Station	9h 40m	06:20	Brussels-South (Gare du Midi)	Fastest
01:35	Lyon - Perrache Bus Station	10h 25m	12:00	Brussels-South (Gare du Midi)	No tags
10:30	Aéroport LYS	16h 30m	03:00	Brussels North Train Station	No tags
03:35	Lyon - Perrache Bus Station	11h 10m	14:45	Brussels-South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 2 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
02:45	Lyon - Perrache Bus Station	10h 45m	13:30	Brussels-South (Gare du Midi)	Cheapest
20:40	Lyon - Perrache Bus Station	9h 40m	06:20	Brussels-South (Gare du Midi)	Fastest
00:20	Lyon - Perrache Bus Station	10h 5m	10:25	Brussels-South (Gare du Midi)	No tags
08:30	Aéroport LYS	18h 30m	03:00	Brussels North Train Station	No tags
01:35	Lyon - Perrache Bus Station	10h 25m	12:00	Brussels-South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 3 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
15:20	Lyon - Perrache Bus Station	10h 53m	02:13	Brussels-South (Gare du Midi)	Cheapest
20:40	Lyon - Perrache Bus Station	9h 40m	06:20	Brussels-South (Gare du Midi)	Fastest
01:35	Lyon - Perrache Bus Station	10h 25m	12:00	Brussels-South (Gare du Midi)	No tags
11:00	Aéroport LYS	16h 35m	03:35	Brussels North Train Station	No tags
02:45	Lyon - Perrache Bus Station	10h 45m	13:30	Brussels-South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 4 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:35	Lyon - Perrache Bus Station	13h 55m	17:30	Brussels-South (Gare du Midi)	Cheapest
01:20	Lyon - Perrache Bus Station	10h 40m	12:00	Brussels-South (Gare du Midi)	Fastest
23:59	Lyon - Perrache Bus Station	12h 1m	12:00	Brussels-South (Gare du Midi)	No tags
11:00	Aéroport LYS	16h 35m	03:35	Brussels North Train Station	No tags
17:55	Aéroport LYS	21h 15m	15:10	Brussels North Train Station	No tags

Next departures from Lyon to Brussels on 5 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
08:35	Lyon - Perrache Bus Station	11h 10m	19:45	Brussels-South (Gare du Midi)	Cheapest
21:30	Perrache	10h 45m	08:15	Brussels South (Gare du Midi)	Fastest
08:35	Lyon - Perrache Bus Station	11h 20m	19:55	Brussels North Train Station	No tags
11:00	Aéroport LYS	17h 45m	04:45	Brussels North Train Station	No tags
16:30	Aéroport LYS	15h 45m	08:15	Brussels South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 6 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
06:20	Lyon - Perrache Bus Station	11h 10m	17:30	Brussels-South (Gare du Midi)	Cheapest
21:30	Perrache	10h 45m	08:15	Brussels South (Gare du Midi)	Fastest
00:30	Lyon - Perrache Bus Station	11h 30m	12:00	Brussels-South (Gare du Midi)	No tags
10:30	Aéroport LYS	17h 5m	03:35	Brussels North Train Station	No tags
08:35	Lyon - Perrache Bus Station	11h 10m	19:45	Brussels-South (Gare du Midi)	No tags

Next departures from Lyon to Brussels on 7 November
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
06:20	Lyon - Perrache Bus Station	10h 10m	16:30	Brussels-South (Gare du Midi)	CheapestFastest
00:30	Lyon - Perrache Bus Station	11h 30m	12:00	Brussels-South (Gare du Midi)	No tags
11:00	Aéroport LYS	16h 35m	03:35	Brussels North Train Station	No tags
08:35	Lyon - Perrache Bus Station	11h 10m	19:45	Brussels-South (Gare du Midi)	No tags
16:40	Aéroport LYS	18h 35m	11:15	Brussels North Train Station	No tags

Last refresh of the prices: Today at 2:55 AM CET.

Compare 3 ways to travel from Lyon to Brussels

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

19train per day

4h 13mAverage duration

566 kmDistance

14kgCO₂ emissions

	Average price	Average duration	CO₂ emissions
Bus	Average priceUS$26 - US$156	Average duration11h 50m	CO₂ emissions 14kg CO₂e
Train	Average priceUS$69 - US$265	Average duration4h 13m	CO₂ emissions 14kg CO₂e
Carpool	Average priceUS$44 - US$101	Average duration7h 30m	CO₂ emissions 24kg CO₂e

Bus Lyon to Brussels: Trip Overview

Average ticket priceUS$52

Average bus trip duration11h 50m

Number of daily buses17

Earliest bus departure00:20

Distance572 km

Latest bus departure23:59

Compare bus companies

FlixBus

3.5/511 125 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

BlaBlaCar Bus

3.5/511 067 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

WiFi2.6

BE Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Lyon to Brussels Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Lyon to Brussels.

We make sure you can find a bus service from Lyon to Brussels from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Brussels will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Lyon and Brussels?

Stops in Lyon

A - Perrache

B - Lyon Airport

C - Lyon

D - Quai de Saoune

E - Villeurbanne INSA

F - Les Charrières

Stops in Brussels

A - Brussels South (Gare du Midi)

B - Brux-Nord

C - Congrès

D - Centrale

Frequently asked questions on the trip Lyon - Brussels

How much does a bus ticket from Lyon to Brussels cost?
The bus ticket price from Lyon to Brussels starts at US$26. The best way to find cheap bus tickets from Lyon to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Lyon to Brussels?
The average travel time between Lyon and Brussels is around 11h 50m, although the fastest bus will take about 8h 40m. This is the time it takes to travel the 569 km that separates the two cities.
How many daily bus connections are there between Lyon and Brussels?
The number of buses from Lyon to Brussels can differ depending on the day of the week. On average, there are 17 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Lyon to Brussels by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Lyon to Brussels?
When taking the bus from Lyon to Brussels, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Lyon to Brussels?
Buses travelling between Lyon and Brussels leave from Perrache or Lyon Airport and arrive at Brussels South (Gare du Midi), Brux-Nord, Congrès.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

29/10

US$88

30/10

US$78

Today

US$48

01/11

US$60

02/11

US$66

03/11

US$31

04/11

US$29

05/11

US$31

The cheapest trip from Lyon to Brussels was searched and found on 04 Nov 2025 with a price of US$29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels as early as possible.

You can expect to pay from US$29 to US$178 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$29, which is on 2025-11-04.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Lyon to Brussels but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Brussels, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Lyon to Brussels will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lyon to Brussels.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Lyon to Brussels?

The bus is the cheapest travel choice for this destination

Vehicle type	Travel time	Avg price	Daily departures
Vehicle typeBus	Travel time11h 50m	Avg priceUS$52	Daily departures17
Vehicle typeTrain	Travel time4h 13m	Avg priceUS$160	Daily departures19
Vehicle typeCarpool	Travel time7h 30m	Avg priceUS$61	Daily departures1

Will you be returning to Lyon by bus?

Bus from Brussels to Lyon

You can also go to Brussels by train

Train from Lyon to Brussels

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Find coaches from Lyon to Brussels