Next departures for Lyon to Brussels on January 10
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Cheapest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Fastest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Bus
Aéroport LYS
Brussels North Train Station
No tags
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Next departures for Lyon to Brussels on January 11
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Cheapest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Fastest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Bus
Aéroport LYS
Brussels North Train Station
No tags
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Next departures for Lyon to Brussels on January 12
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Cheapest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
Fastest
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Bus
Aéroport LYS
Brussels North Train Station
No tags
Bus
Lyon - Perrache Bus Station
Brussels-South (Gare du Midi)
No tags
Next departures for Lyon to Brussels on January 13
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon (Gerland)
Brussels-South (Gare du Midi)
Cheapest
Bus
Lyon (Gerland)
Brussels South (Gare du Midi)
Fastest
Bus
Lyon (Gerland)
Brussels-South (Gare du Midi)
No tags
Bus
Aéroport LYS
Brussels North Train Station
No tags
Bus
Lyon (Gerland)
Brussels-South (Gare du Midi)
No tags
Last refresh of the prices: Today at 2:16 AM CET.
Compare 3 ways to go from Lyon to Brussels
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Brussels. The journey takes about 4 hours 13 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11357 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $25
Frequently asked questions about traveling from Lyon to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lyon to Brussels?
The cheapest bus tickets from Lyon to Brussels start from $25. The average price for this route is around $46. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lyon to Brussels?
The average bus trip duration from Lyon to Brussels is 11h 30m, covering a distance of 354 miles (570 km). The quickest bus can get you there in 8h 40m and is operated by BlaBlaCar Bus.
Which bus companies service the Lyon to Brussels route?
Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Lyon to Brussels?
The earliest bus departs from Lyon to Brussels at 12:10am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Lyon to Brussels?
A bus trip from Lyon to Brussels generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lyon to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11278 reviews.
Which bus company has the best Wi-Fi from Lyon to Brussels?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Lyon to Brussels?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lyon to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
01/06
$60
01/07
$135
Today
$30
01/09
$33
01/10
$26
01/11
$23
01/12
$23
01/13
$23
The cheapest trip from Lyon to Brussels was searched and found on Jan 11, 2026 with a price of $23
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels, as early as possible.
You can expect to pay from $23 to $137 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $23 which is on 2026-01-11.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Lyon to Brussels?
The Bus is the cheapest travel choice for this destination
The cheapest trip from Lyon to Brussels was searched and found on Jan 11, 2026 with a price of $23
The Bus is the cheapest travel choice for this destination
