Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Minneapolis | La Crosse (U of WI) | Cheapest | ||||
| Bus | Minneapolis (Mall of America) | 314 Jay St., La Crosse | Fastest | ||||
| Bus | Minneapolis | La Crosse (U of WI) | No tags | ||||
| Bus | MSP Airport T1 (Minneapolis International Airport) | La Crosse (U of WI) | No tags | ||||
| Bus | MSP Airport T1 (Minneapolis International Airport) | La Crosse (U of WI) | No tags |
Last refresh of the prices: Last Friday at 4:22 PM CST.
Get from Minneapolis to La Crosse
The journey takes about 4 hours 20 minutes, and with fares starting at just R 493, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 766 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Jefferson Lines ticket prices on this trip start at R 493
Jefferson Lines Minneapolis La Crosse recent customer reviews
First time on bus. Both people in Minneapoles terminal very helpful as I had questions. Driver and assistant also nice.
David S.
Frequently asked questions about travelling from Minneapolis to La Crosse, WI by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Minneapolis to La Crosse?
The cheapest bus tickets from Minneapolis to La Crosse start at R 493. The average price for this route is around R 493. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Minneapolis to La Crosse?
The average bus journey time from Minneapolis to La Crosse is 4h 20m, covering a distance of 203 km. The fastest bus gets you there in 3h 10m and is operated by Jefferson Lines.
Which bus companies service the Minneapolis to La Crosse route?
Several major bus companies operate on this route with 9 buses available per day.
What is the earliest and latest departure time for the bus from Minneapolis to La Crosse?
The earliest bus departs from Minneapolis to La Crosse at 09:30. And the latest bus departs at 15:15.
What are the CO₂ emissions for the bus trip from Minneapolis to La Crosse?
A bus trip from Minneapolis to La Crosse produces an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Minneapolis to La Crosse, WI was searched and found on 24 Jan 2026 with a price of R 477To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Minneapolis to La Crosse, WI as early as possible.
You can expect to pay from R 477 to R 1 364 for a bus ticket from Minneapolis to La Crosse, WI based on the last 2 days. You can expect to find the cheapest price for the trip at R 477, which is on 2026-01-28.
