Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Brussels North Train Station | Cheapest | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | Fastest | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags |
Last refresh of the prices: Today at 4:11 PM CET.
Compare 2 ways to travel from Rome to Brussels
Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 15 hours and with fares starting at just R 2 545, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 1 193 - R 6 425 | Average duration1d 6h | 29kg CO₂e | ||
Carpool | Average priceR 2 545 - R 2 545 | Average duration15h | 49kg CO₂e |
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Where are the popular stops in Rome and Brussels?
Frequently asked questions about travelling from Rome to Brussels by bus
How much does a bus ticket from Rome to Brussels cost?
The bus ticket price from Rome to Brussels starts at R 1 193. The best way to find cheap bus tickets from Rome to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Rome to Brussels?
The average travel time between Rome and Brussels is around 1d 6h, although the fastest bus will take about 22h 30m. This is the time it takes to travel the 1175 km that separates the two cities.
How many daily bus connections are there between Rome and Brussels?
The number of buses from Rome to Brussels can differ depending on the day of the week. On average, there are 17 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Rome to Brussels by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Rome to Brussels?
When taking the bus from Rome to Brussels, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Rome to Brussels?
Buses travelling between Rome and Brussels leave from Rome Tiburtina Bus Station or Rome Ciampino Airport and arrive at Brussels South (Gare du Midi), Brux-Nord, Congrès.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brussels was searched and found on 21 Nov 2025 with a price of R 1 426To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels as early as possible.
You can expect to pay from R 1 426 to R 3 770 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 426, which is on 2025-11-21.