Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Brussels-South (Gare du Midi) | CheapestFastest | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags |
Last refresh of the prices: Yesterday at 7:19 PM CEST.
Get from Rome to Brussels
The journey takes about 1 day, 5 hours 50 minutes, and with fares starting at just PLN 284, it presents an excellent value for a comfortable ride.
Where are the popular stops in Rome and Brussels?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - DPachecolaan 5, 1000 Brussel, Belgium
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Frequently asked questions about travelling from Rome to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Brussels?
The cheapest bus tickets from Rome to Brussels start from PLN 284. The average price for this route is around PLN 461. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Brussels?
The average bus travel time from Rome to Brussels is 1d 5h, covering a distance of 1177 km. The quickest bus can get you there in 22h 30m and is operated by FlixBus.
Which bus companies service the Rome to Brussels route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What are the earliest and latest departure times for the bus from Rome to Brussels?
The earliest bus departs from Rome to Brussels at 12:15am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Brussels?
A bus trip from Rome to Brussels generates an estimated 29.424599999999998 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rome to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1074 reviews.
Which bus company has the best Wi-Fi from Rome to Brussels?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Rome to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Rome to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brussels was searched and found on May 11, 2026 with a price of PLN 299To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels, as early as possible.
You can expect to pay from PLN 299 to PLN 1,028 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 299 which is on 2026-05-11.
