How much is the bus ticket from Rome to Brussels?

The cheapest bus tickets from Rome to Brussels start from $104. The average price for this route is around $222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Rome to Brussels?

The average bus travel time from Rome to Brussels is 1d 5h, covering a distance of 1182 km. The quickest bus can get you there in 22h 30m and is operated by FlixBus .

Which bus companies service the Rome to Brussels route?

Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet .

What are the earliest and latest departure times for the bus from Rome to Brussels?

The earliest bus departs from Rome to Brussels at 12:10am. And the latest bus departs at 11:50pm.

What are the CO₂ emissions for the bus trip from Rome to Brussels?

A bus trip from Rome to Brussels generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Rome to Brussels?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1062 reviews.

Which bus company has the best Wi-Fi from Rome to Brussels?

Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.

Which bus company has the best on-time performance from Rome to Brussels?

According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Rome to Brussels?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Rome to Brussels from $185 | Refundable Tickets

Next bus departures

Next departures for Rome to Brussels on December 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:45pm	Rome Tiburtina Bus Station	1d 9h	8:15am	Brussels South (Gare du Midi)	Cheapest
Bus	8:00pm	Rome Tiburtina Bus Station	1d	8:35pm	Brussels North Train Station	Fastest
Bus	11:50pm	Rome Tiburtina Bus Station	1d 8h	8:40am	Brussels North Train Station	No tags
Bus	5:25pm	Rome Anagnina	1d 3h	8:35pm	Brussels North Train Station	No tags
Bus	5:25pm	Rome Anagnina	1d 6h	11:30pm	Brussels South (Gare du Midi)	No tags

Next departures for Rome to Brussels on December 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:20pm	Rome Tiburtina Bus Station	1d 1h	4:30pm	Brussels-South (Gare du Midi)	CheapestFastest
	Bus	3:20pm	Rome Tiburtina Bus Station	1d 4h	7:55pm	Brussels North Train Station	No tags

Next departures for Rome to Brussels on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:20pm	Rome Tiburtina Bus Station	1d 1h	4:30pm	Brussels-South (Gare du Midi)	CheapestFastest
	Bus	3:20pm	Rome Tiburtina Bus Station	1d 4h	7:55pm	Brussels North Train Station	No tags

Next departures for Rome to Brussels on December 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:45am	Aeroporto Ciampino Airport (CIA)	1d	11:35am	Brussels North Train Station	Cheapest
Bus	10:10am	Rome Tiburtina Bus Station	22h 30m	8:40am	Brussels North Train Station	Fastest
Bus	3:20pm	Rome Tiburtina Bus Station	1d 1h	4:30pm	Brussels-South (Gare du Midi)	No tags
Bus	1:00pm	Rome Tiburtina Bus Station	1d 17h	6:00am	Brussels South (Gare du Midi)	No tags
Bus	12:10am	Rome Tiburtina Bus Station	1d 2h	3:00am	Brussels North Train Station	No tags

Next departures for Rome to Brussels on December 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:55pm	Rome Tiburtina Bus Station	1d 8h	7:20am	Brussels South (Gare du Midi)	Cheapest
Bus	10:10am	Rome Tiburtina Bus Station	22h 30m	8:40am	Brussels North Train Station	Fastest
Bus	3:20pm	Rome Tiburtina Bus Station	1d 1h	4:30pm	Brussels-South (Gare du Midi)	No tags
Bus	12:10am	Rome Tiburtina Bus Station	1d 2h	3:00am	Brussels North Train Station	No tags
Bus	3:20pm	Rome Tiburtina Bus Station	1d 4h	7:55pm	Brussels North Train Station	No tags

Next departures for Rome to Brussels on December 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:00pm	Rome Fiumicino Airport	1d 8h	6:00am	Brussels North Train Station	Cheapest
Bus	9:25am	Rome Tiburtina Bus Station	23h 15m	8:40am	Brussels North Train Station	Fastest
Bus	3:20pm	Rome Tiburtina Bus Station	1d 1h	4:30pm	Brussels-South (Gare du Midi)	No tags
Bus	12:10am	Rome Tiburtina Bus Station	1d 3h	3:35am	Brussels North Train Station	No tags
Bus	8:30am	Rome Tiburtina Bus Station	1d	8:30am	Brussels North Train Station	No tags

Last refresh of the prices: Yesterday at 8:32 PM CET.

Compare 2 ways to go from Rome to Brussels

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 15 hours, and with fares starting at just $204, it presents an excellent value for a comfortable ride.

1carpool per day

15hAverage Duration

1174 kmDistance

49kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$104 - $535	Average Duration1d 5h	CO₂ emissions 30kg CO₂e
Carpool	Average Price$204 - $204	Average Duration15h	CO₂ emissions 49kg CO₂e

Where are the popular stops in Rome and Brussels?

Stops in Rome

A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
B
Rome Ciampino Airport
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Compare bus companies

FlixBus

3.5/511,705 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

BlaBlaCar Bus

3.5/511,276 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.6

RegioJet

4/51,062 reviews

Staff4.5

Timeliness4

Cleanliness4.4

Wifi3.8

BE Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Rome to Brussels by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Rome to Brussels?
The cheapest bus tickets from Rome to Brussels start from $104. The average price for this route is around $222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Brussels?
The average bus travel time from Rome to Brussels is 1d 5h, covering a distance of 1182 km. The quickest bus can get you there in 22h 30m and is operated by FlixBus.
Which bus companies service the Rome to Brussels route?
Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What are the earliest and latest departure times for the bus from Rome to Brussels?
The earliest bus departs from Rome to Brussels at 12:10am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Brussels?
A bus trip from Rome to Brussels generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rome to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Rome to Brussels?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Rome to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Rome to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-21

$312

12-22

$210

Today

$185

12-24

$195

12-25

$201

12-26

$287

12-27

$237

12-28

$214

The cheapest trip from Rome to Brussels was searched and found on Dec 23, 2025 with a price of $185

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels, as early as possible.

You can expect to pay from $185 to $541 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $195 which is on 2025-12-24.