Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Brussels North Train Station | CheapestFastest | ||||
 | Bus | Rome Tiburtina Bus Station | Brussels-South (Gare du Midi) | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Brussels North Train Station | No tags |
Last refresh of the prices: Last Wednesday at 17:54 CET.
Compare 2 ways to travel from Rome to Brussels
Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 15 hours and with fares starting at just £114, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£54 - £286 | Average duration1d 6h | 29kg CO₂e | ||
Carpool | Average price£114 - £114 | Average duration15h | 49kg CO₂e |
Where are the popular stops in Rome and Brussels?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about travelling by bus from Rome to Brussels
What's the distance between Rome and Brussels by coach?
The distance between Rome and Brussels by coach is approximately 729 miles (1175 km).
How can I travel from Rome to Brussels avoiding air travel?
You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brussels was searched and found on 26 Nov 2025 with a price of £63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels as early as possible.
You can expect to pay from £63 to £149 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £63, which is on 2025-11-26.
