Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Rome Tiburtina Bus Station | Lyon - Perrache Bus Station | Cheapest | |||||
 | Rome Tiburtina Bus Station | Lyon Lyon Perrache Bus Station | Fastest | |||||
 | Rome Tiburtina Bus Station | de Perrache - Galerie A | No tags | |||||
| Rome Tiburtina Bus Station | Lyon Lyon Perrache Bus Station | No tags | |||||
| Rome Tiburtina Bus Station | Aéroport LYS | No tags |
Last refresh of the prices: Last Sunday at 12:37 PM CET.
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Compare 3 ways to travel from Rome to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 11 hours 40 minutes and with fares starting at just R 935, it presents an excellent value for a comfortable ride.
Bus Rome to Lyon: Trip Overview
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Rome to Lyon Bus
Busbud helps you find a bus from Rome to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Rome to Lyon from the most reliable bus companies operating this trip.
Discover how much the bus trip from Rome to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Rome and Lyon?
Frequently asked questions on the trip Rome - Lyon
How much does a bus ticket from Rome to Lyon cost?
The bus ticket price from Rome to Lyon starts at R 612. The best way to find cheap bus tickets from Rome to Lyon is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Rome to Lyon?
The average travel time between Rome and Lyon is around 17h 10m, although the fastest bus will take about 14h 30m. This is the time it takes to travel the 748 km that separates the two cities.
How many daily bus connections are there between Rome and Lyon?
The number of buses from Rome to Lyon can differ depending on the day of the week. On average, there are 13 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Rome to Lyon by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Rome to Lyon?
When taking the bus from Rome to Lyon, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, Itabus.
What are the departure and arrival stations when taking the bus from Rome to Lyon?
Buses travelling between Rome and Lyon leave from Rome Ciampino Airport or Rome Tiburtina Bus Station and arrive at Perrache, Lyon Airport, Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Lyon was searched and found on 07 Nov 2025 with a price of R 718To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon as early as possible.
You can expect to pay from R 718 to R 3 374 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 718, which is on 2025-11-07.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rome and Lyon!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Lyon, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Rome to Lyon will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Lyon.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Rome
Buses Leaving from Rome
- Bus from Rome to Como
- Coach Rome - Fiumicino
- Bus Rome - Naples
- Bus from Rome to Tours
- Coach Rome - Outlet
- Bus Rome - Amalfi
- Bus from Rome to Sant'Agata di Militello
- Coach Rome - Pozzallo
- Bus Rome - Calda
- Bus from Rome to Perugia
- Coach Rome - Siano
- Bus Rome - Ragusa
- Bus from Rome to Guardia Piemontese
- Coach Rome - Rosarno
- Bus Rome - Ruvo di Puglia
Buses Going to Rome
- Bus from Milano to Rome
- Coach Venice - Rome
- Bus Civitavecchia - Rome
- Bus from Rimini to Rome
- Coach Barcelona - Rome
- Bus Nice - Rome
- Bus from Palizzi to Rome
- Coach Ortona - Rome
- Bus Piano Lago - Rome
- Bus from Villaggio Boncore to Rome
- Coach Catania - Rome
- Bus Metaponto - Rome
- Bus from Grottaglie to Rome
- Coach Chivasso - Rome
- Bus Silvi - Rome
Popular Buses Connecting Lyon
Buses Leaving from Lyon
- Bus from Lyon to Marseille
- Coach Lyon - Saint-Étienne
- Bus Lyon - Lens
- Bus from Lyon to Reims
- Coach Lyon - Rennes
- Bus Lyon - Auxerre
- Bus from Lyon to Colmar
- Coach Lyon - Fréjus
- Bus Lyon - Grimaud
- Bus from Lyon to Thiers
- Coach Lyon - Vivy
- Bus Lyon - Les Sables-d'Olonne
- Bus from Lyon to Carnac
- Coach Lyon - Vieux-Boucau-les-Bains
- Bus Lyon - Nancy
Buses Going to Lyon
- Bus from Saint-Étienne to Lyon
- Coach Nice - Lyon
- Bus Montpellier - Lyon
- Bus from Le Havre to Lyon
- Coach Utrecht - Lyon
- Bus Brest - Lyon
- Bus from Le Cannet to Lyon
- Coach Aime - Lyon
- Bus Sedan - Lyon
- Bus from Bollène to Lyon
- Coach Lille - Lyon
- Bus Lorient - Lyon
- Bus from Rolampont to Lyon
- Coach Strasbourg - Lyon
- Bus Saint-Jean-de-Monts - Lyon