Is there a way to reach Lyon from Rome without flying?

Both buses and trains are available for traveling between these two cities. Both are easy and sustainable ways to travel to Lyon. You can also use carpool services and share a car ride with other travelers.

How long is the bus ride from Rome to Lyon?

Traveling from Rome to Lyon takes about 16h 35m on average, although the fastest bus will take 14h 25m, on average. This is the time it takes to travel the 464 miles (748 km) that separate the two cities.

What is the distance between Rome and Lyon?

Rome and Lyon are 464 miles (748 km) apart.

What are the departure and arrival stations when taking the bus from Rome to Lyon?

If you're headed to Lyon from Rome, chances are that your bus will depart from Rome Tiburtina Bus Station and arrive at Perrache. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What is the cheapest way to get from Rome to Lyon?

If you want the cheapest way to travel this route, go for the bus. The lowest price for the bus on this route is $35.

What is the ticket price for the bus trip from Rome to Lyon?

The bus ticket costs $91 on average. In the last 30 days, the prices ranged from $35 to $266, so it's good to do your research before booking.

What are the best sights and things to do in Lyon?

Once in Lyon, you can start exploring the city and discover its surroundings. The top sights and things to do are Musée des Beaux Arts, Musée d’Art Contemporain, Opéra de Lyon, Institut Lumière and Musée des Tissus.

Rome to Lyon Bus Tickets

TodayMay 7

TomorrowMay 8

from $53

FriMay 9

from $59

SatMay 10

from $66

SunMay 11

from $82

MonMay 12

from $53

TueMay 13

from $53

WedMay 14

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: May 8 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: May 8 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m
Departure time: May 8 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: May 8 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m
Departure time: May 8 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: May 8 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m
Departure time: May 8 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: May 8 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m
Departure time: May 8 at 9:45pm
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: May 9 at 12:55pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 15h 10m

Accepted payments

Compare 3 ways to go from Rome to Lyon.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$35 - $266	Average Duration16h 35m	CO₂ emissions 19kg CO₂e5 out of 5 stars	Cheapest
Train	Average Price$166 - $585	Average Duration8h 42m	CO₂ emissions 18kg CO₂e5 out of 5 stars	FastestMost eco-friendly
Carpool	Average Price$64 - $109	Average Duration12h	CO₂ emissions 31kg CO₂e4 out of 5 stars

Busbud recommends taking the train from Rome to Lyon

Among the sustainable travel choices, the train stands out as the good way to reach Lyon. The journey takes about 8 hours 42 minutes and with fares starting at just $166, it presents an excellent value for a comfortable ride.

1train per day

8h 42mAverage Duration

$166Cheapest ticket

18kgCO₂ emissions

Bus Rome to Lyon: Trip Overview

Average ticket price$91

Average bus trip duration16h 35m

Number of daily buses10

Earliest bus departure12:10am

Distance465 miles (750 km)

Latest bus departure11:50pm

Compare bus companies

FlixBus

3.5/58,535 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Itabus

4/5884 reviews

Staff4.3

Timeliness3.1

Cleanliness4.3

Wifi3.1

RegioJet

4/51,021 reviews

Staff4.4

Timeliness4

Cleanliness4.4

Wifi3.8

BlaBlaCar Bus

3.5/510,183 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.5

FR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Trenitalia, Sindbad, MarinoBus, Infobus

Rome to Lyon Bus

Busbud helps you find a bus from Rome to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Rome to Lyon from the most reliable bus companies operating this trip.

Discover how much the bus trip from Rome to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Rome and Lyon?

Stops in Rome

A - Rome Tiburtina Bus Station

B - Rome Ciampino Airport

C - Rome Fiumicino Airport

D - Castro Pretorio

E - Roma

F - Anagnina

Stops in Lyon

A - Perrache

B - Lyon Airport

C - Les Charrières

D - Gare Routière - Lyon Part-Dieu

E - Lyon

F - Quai de Saoune

Frequently asked questions for your trip Rome - Lyon

Is there a way to reach Lyon from Rome without flying?
How long is the bus ride from Rome to Lyon?
What is the distance between Rome and Lyon?
What are the departure and arrival stations when taking the bus from Rome to Lyon?
What is the cheapest way to get from Rome to Lyon?
What is the ticket price for the bus trip from Rome to Lyon?
What are the best sights and things to do in Lyon?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/05

$64

05/06

$66

Today

$163

05/08

$53

05/09

$59

05/10

$65

05/11

$82

05/12

$53

The cheapest trip from Rome to Lyon was searched and found on May 8, 2025 with a price of $53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon, as early as possible.

You can expect to pay from $53 to $219 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-05-08.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rome and Lyon!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Lyon, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rome to Lyon will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Lyon.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Rome to Lyon?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time16h 35m	Avg Price$91	Daily Departures10
Vehicle TypeTrain	Travel Time8h 42m	Avg Price$269	Daily Departures1
Vehicle TypeCarpool	Travel Time12h	Avg Price$104	Daily Departures1

Will you be returning to Rome by bus?

Bus from Rome to Lyon

You can also go to Lyon by train

Train from Rome to Lyon

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Rome to Lyon

Cheap buses leaving tomorrow

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 3 ways to go from Rome to Lyon.

Bus Rome to Lyon: Trip Overview

Compare bus companies

Rome to Lyon Bus

Where are the popular stops in Rome and Lyon?

Frequently asked questions for your trip Rome - Lyon

Is there a way to reach Lyon from Rome without flying?

How long is the bus ride from Rome to Lyon?

What is the distance between Rome and Lyon?

What are the departure and arrival stations when taking the bus from Rome to Lyon?

What is the cheapest way to get from Rome to Lyon?

What is the ticket price for the bus trip from Rome to Lyon?

What are the best sights and things to do in Lyon?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Rome to Lyon?

Will you be returning to Rome by bus?

You can also go to Lyon by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Rome

Buses Leaving from Rome

Buses Going to Rome

Popular Buses Connecting Lyon

Buses Leaving from Lyon

Buses Going to Lyon

Popular routes in this country

Popular airport transfers