Find coaches from Rome to Lyon

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Today28 Jun
from US$78
Tomorrow29 Jun
from US$70
Mon30 Jun
from US$63
Tue1 Jul
from US$66
Wed2 Jul
from US$73
Thu3 Jul
Fri4 Jul
Sat5 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 29 June at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 29 June at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 29 June at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 29 June at
    Destination city: Lyon
    Destination location: Lyon Lyon Perrache Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 29 June at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 29 June at
    Destination city: Lyon
    Destination location: Lyon Lyon Perrache Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 29 June at
    Destination city: Lyon
    Destination location: Perrache
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

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Compare 3 ways to travel from Rome to Lyon

Bus
Average priceUS$30 - US$260Average duration16h 55m
19kg CO₂e5 out of 5 stars
Cheapest
Train
Average priceUS$166 - US$337Average duration8h 42m
18kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Carpool
Average priceUS$64 - US$109Average duration12h
31kg CO₂e4 out of 5 stars
busbud logoBusbud recommends taking the train from Rome to Lyon

Among the sustainable travel choices, the train stands out as a good way to reach Lyon. The journey takes about 8 hours 42 minutes and with fares starting at just US$166, it presents an excellent value for a comfortable ride.

1train per day
8h 42mAverage duration
US$166Cheapest ticket
18kgCO₂ emissions

Bus Rome to Lyon: Trip Overview

Average ticket priceUS$87
Average bus trip duration16h 55m
Number of daily buses12
Earliest bus departure00:10
Distance459 miles
Latest bus departure23:50

Rome to Lyon Bus

Busbud helps you find a bus from Rome to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Rome to Lyon from the most reliable bus companies operating this trip.

Discover how much the bus trip from Rome to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rome - Lyon

  1. What's the distance between Rome and Lyon by coach?

    The journey from Rome to Lyon by coach covers an approximate distance of 464 miles (748 km).

  2. What is the best way to go from Rome to Lyon without flying?

    To travel from Rome to Lyon without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/06
US$56
27/06
US$85
Today
US$60
29/06
US$66
30/06
US$57
01/07
US$61
02/07
US$67
03/07
US$54
busbud logoThe cheapest trip from Rome to Lyon was searched and found on 3 Jul 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon as early as possible.

You can expect to pay from US$54 to US$181 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$54, which is on 2025-07-03.

Usually Flixbus (IT), STUDENT AGENCY k.s. - 1177309001 - Transport Conditions: https://www.regiojet.com/en/documents/transport-rules-and-conditions/contractual-transport-terms-and-conditions-regiojet-buses.pdf will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rome and Lyon!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Lyon, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Rome to Lyon will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Lyon.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Rome to Lyon?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rome by bus?

Bus from Rome to Lyon

You can also go to Lyon by train

Train from Rome to Lyon

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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