Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santander (Estacion de Autobuses) | Lyon | Cheapest | ||||
| Bus | Santander (Estacion de Autobuses) | Lyon | Fastest | ||||
| Bus | SANTANDER | LYON | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Lyon | No tags |
Last refresh of the prices: Last Sunday at 2:42 PM CEST.
Get from Santander to Lyon
The journey takes about 19 hours 5 minutes, and with fares starting at just CLP 61 355, it presents an excellent value for a comfortable ride.
Bus stations and stops in Santander and Lyon
Stops in Santander
- A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain - C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Santander to Lyon by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santander to Lyon?
The cheapest bus tickets from Santander to Lyon start at CLP 61 355. The average price for this route is around CLP 89 904. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santander to Lyon?
The average bus journey time from Santander to Lyon is 19h 5m, covering a distance of 730 km. The fastest bus gets you there in 13h 59m and is operated by ALSA.
Which bus companies service the Santander to Lyon route?
Several major bus companies operate on this route with 3 buses available per day, including services from ALSA, FlixBus, Lux Reisen.
What is the earliest and latest departure time for the bus from Santander to Lyon?
The earliest bus departs from Santander to Lyon at 02:30. And the latest bus departs at 20:45.
What are the CO₂ emissions for the bus trip from Santander to Lyon?
A bus trip from Santander to Lyon produces an estimated 18.2271 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Santander to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 63224 reviews.
Which bus company has the best Wi-Fi from Santander to Lyon?
Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.
Which bus company offers the most punctual service from Santander to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santander to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Lux Reisen, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lyon was searched and found on 12 Aug 2026 with a price of CLP 54 609To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon as early as possible.
You can expect to pay from CLP 54 609 to CLP 126 406 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 77 590, which is on 2026-08-14.
