Bus Tickets from Santander to Lyon

Find affordable bus tickets from Santander to Lyon with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Compare 2 ways to go from Santander to Lyon

Bus
Average PriceUS$105 - US$125Average Duration13h 14m
18kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$49 - US$49Average Duration9h 30m
31kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Santander to Lyon

Among the sustainable travel choices, the bus stands out as a good way to reach Lyon. The journey takes about 13 hours 14 minutes, and with fares starting at just US$105, it presents an excellent value for a comfortable ride.

1bus per day
13h 14mAverage Duration
US$105Cheapest ticket
18kgCO₂ emissions

Bus Santander to Lyon: Trip Overview

Average Ticket PriceUS$123
Average Bus Trip Duration13h 14m
Number of daily buses1
Earliest bus departure6:50pm
Distance729 km
Latest bus departure8:45pm

Santander to Lyon Bus

Busbud helps you find a bus from Santander to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Santander to Lyon will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santander to Lyon, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santander - Lyon

  1. What is the distance between Santander and Lyon?

    Santander and Lyon are 732 km (454 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Santander to Lyon?

    Buses departing from Calle Navas de Tolosa, 2 in Santander will take you to Perrache in Lyon.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-26
No data
06-27
US$77
Today
No data
06-29
No data
06-30
No data
07-01
No data
07-02
US$60
07-03
No data
busbud logoThe cheapest trip from Santander to Lyon was searched and found on Jul 2, 2025 with a price of US$60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon, as early as possible.

You can expect to pay from US$60 to US$173 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$60 which is on 2025-07-02.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santander and Lyon!

Much more than a mere vehicle taking you from Santander to Lyon, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santander to Lyon that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santander to Lyon while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Santander by bus?

Bus from Santander to Lyon

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Santander

Buses Leaving from Santander

Buses Going to Santander

Popular Buses Connecting Lyon

Buses Leaving from Lyon

Buses Going to Lyon