Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | SANTANDER | LYON | Cheapest | ||||
| Bus | SANTANDER | LYON | Fastest | ||||
BlaBlaCar Bus - Alsa + BlaBlaCar Bus | Bus | Santander (Estacion de Autobuses) | Lyon - Gerland Bus Station | No tags |
Last refresh of the prices: Last Tuesday at 1:43 PM CEST.
Get from Santander to Lyon
The journey takes about 19 hours 5 minutes and with fares starting at just RUB 5,893, it presents an excellent value for a comfortable ride.
Bus stations and stops in Santander and Lyon
Stops in Santander
- A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain - C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about traveling from Santander to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santander to Lyon?
The cheapest bus tickets from Santander to Lyon start from RUB 5,893. The average price for this route is around RUB 8,557. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santander to Lyon?
The average bus trip duration from Santander to Lyon is 19h 5m, covering a distance of 453 miles (730 km). The quickest bus can get you there in 13h 59m and is operated by ALSA.
Which bus companies service the Santander to Lyon route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, ALSA, Lux Reisen.
What is the earliest and latest departure time for the bus from Santander to Lyon?
The earliest bus departs from Santander to Lyon at 2:30am. And the latest bus departs at 8:45pm.
What are the CO₂ emissions for the bus trip from Santander to Lyon?
A bus trip from Santander to Lyon generates an estimated 18.242549999999998 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santander to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 63514 reviews.
Which bus company has the best Wi-Fi from Santander to Lyon?
Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.
Which bus company has the most timely service from Santander to Lyon?
According to Busbud traveler reviews, the most timely bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santander to Lyon?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Lux Reisen, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lyon was searched and found on Sep 8, 2026 with a price of RUB 4,114To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon, as early as possible.
You can expect to pay from RUB 4,114 to RUB 11,466 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at RUB 4,114 which is on 2026-09-08.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
