Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | SANTANDER | LYON | Cheapest | ||||
| Bus | SANTANDER | LYON | Fastest |
Last refresh of the prices: Today at 11:34 CET.
Compare 2 ways to travel from Santander to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 10 hours 50 minutes and with fares starting at just £64, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£56 - £144 | Average duration19h 55m | 18kg CO₂e | ||
Carpool | Average price£64 - £64 | Average duration10h 50m | 31kg CO₂e |
Where are the popular stops in Santander and Lyon?
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about travelling by bus from Santander to Lyon
How far is Lyon from Santander by coach?
The journey from Santander to Lyon by coach covers an approximate distance of 454 miles (732 km).
What is the best way to go from Santander to Lyon without flying?
To travel from Santander to Lyon without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lyon was searched and found on 28 Nov 2025 with a price of £26To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon as early as possible.
You can expect to pay from £26 to £106 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at £26, which is on 2025-11-28.
