Find coaches from Spartanburg to Chicago

Next bus departures

Next departures from Spartanburg to Chicago on 11 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Spartanburg
Chicago 95Th & Dan RyanCheapest
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Chicago 95Th & Dan RyanFastest
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.Bus
Spartanburg
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Spartanburg
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Spartanburg
537-517 W. Jackson BlvdNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Today at 9:48 AM EST.

Compare 2 ways to travel from Spartanburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 21 hours 50 minutes and with fares starting at just R 1 339, it presents an excellent value for a comfortable ride.

10bus per day
21h 50mAverage duration
909 kmDistance
23kgCO₂ emissions
Bus
Average priceR 1 339 - R 5 293Average duration21h 50m
23kg CO₂e
Train
Average priceR 3 315 - R 22 053Average duration1d 6h
83kg CO₂e

Frequently asked questions about travelling from Spartanburg to Chicago by bus

  1. How much does a bus ticket from Spartanburg to Chicago cost?

    The bus ticket price from Spartanburg to Chicago starts at R 1 339. The best way to find cheap bus tickets from Spartanburg to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Spartanburg to Chicago?

    The average travel time between Spartanburg and Chicago is around 21h 50m, although the fastest bus will take about 18h 30m. This is the time it takes to travel the 916 km that separates the two cities.

  3. How many daily bus connections are there between Spartanburg and Chicago?

    The number of buses from Spartanburg to Chicago can differ depending on the day of the week. On average, there are 10 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Spartanburg to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Spartanburg to Chicago?

    When taking the bus from Spartanburg to Chicago, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Spartanburg to Chicago?

    Buses travelling between Spartanburg and Chicago leave from Super Acapulco or Spartanburg Bus Stop and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/11
R 2 531
09/11
R 3 059
Today
No data
11/11
R 2 742
12/11
No data
13/11
No data
14/11
No data
15/11
No data
busbud logoThe cheapest trip from Spartanburg to Chicago was searched and found on 08 Nov 2025 with a price of R 2 531

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago as early as possible.

You can expect to pay from R 2 531 to R 3 059 for a bus ticket from Spartanburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 742, which is on 2025-11-11.

What's the cheapest way to go from Spartanburg to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

People from around the world trust Busbud

‌

Popular Buses Connecting Spartanburg

Buses Leaving from Spartanburg

Buses Going to Spartanburg

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago