Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | 1116 Woodruff Rd | CheapestFastest |
Last refresh of the prices: Yesterday at 3:24 PM EST.
Compare 2 ways to travel from Syracuse to Greenville
Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 22 hours 18 minutes and with fares starting at just R 3 384, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 1 922 - R 5 760 | Average duration22h 15m | 26kg CO₂e | ||
Train | Average priceR 3 384 - R 3 889 | Average duration22h 18m | 97kg CO₂e |
Where are the popular stops in Syracuse and Greenville?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling from Syracuse, US to Greenville, SC by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Syracuse to Greenville?
The cheapest bus tickets from Syracuse to Greenville start at R 1 922. The average price for this route is around R 3 993. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Syracuse to Greenville?
The average bus journey time from Syracuse to Greenville is 22h 15m, covering a distance of 1059 km. The fastest bus gets you there in 21h 50m and is operated by FlixBus.
Which bus companies service the Syracuse to Greenville route?
What is the earliest and latest departure time for the bus from Syracuse to Greenville?
The earliest bus departs from Syracuse to Greenville at 09:25. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Syracuse to Greenville?
A bus trip from Syracuse to Greenville produces an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Syracuse to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11799 reviews.
Which bus company has the best Wi-Fi from Syracuse to Greenville?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Syracuse to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Greenville, SC was searched and found on 07 Jan 2026 with a price of R 2 593To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Greenville, SC as early as possible.
