How much does a bus ticket from Syracuse to Greenville cost?

The bus ticket price from Syracuse to Greenville starts at R 1 844. The best way to find cheap bus tickets from Syracuse to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Syracuse to Greenville?

The average travel time between Syracuse and Greenville is around 22h 20m, although the fastest bus will take about 20h 55m. This is the time it takes to travel the 1060 km that separates the two cities.

How many daily bus connections are there between Syracuse and Greenville?

The number of buses from Syracuse to Greenville can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Syracuse to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Syracuse to Greenville?

When taking the bus from Syracuse to Greenville, you can travel comfortably and safely with FlixBus, Greyhound.

What are the departure and arrival stations when taking the bus from Syracuse to Greenville?

Buses travelling between Syracuse and Greenville leave from Regional Transportation Center or Syracuse Airport and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

Bus Syracuse to Greenville from R 1 666 | Refundable Tickets

Next bus departures

Next departures from Syracuse to Greenville on 14 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	21:00	Syracuse (Regional Transportation Center)	22h 40m	19:40	1116 Woodruff Rd	Cheapest
	Bus	15:00	Syracuse (Regional Transportation Center)	22h 15m	13:15	1116 Woodruff Rd	Fastest

Last refresh of the prices: 11/07/2025 EST.

Compare 2 ways to travel from Syracuse to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 22 hours 20 minutes and with fares starting at just R 1 844, it presents an excellent value for a comfortable ride.

3bus per day

22h 20mAverage duration

1059 kmDistance

26kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 1 844 - R 4 684	Average duration22h 20m	CO₂ emissions 26kg CO₂e
Train	Average priceR 3 524 - R 4 050	Average duration22h 18m	CO₂ emissions 97kg CO₂e

Compare bus companies

FlixBus

3.5/511 306 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Based on 11306 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 888

FlixBus Syracuse Greenville recent customer reviews

It depended on the driver, as well as the cleanliness of each individual bus.

Marie S.

28 July 2023

Greyhound

3.5/587 371 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Syracuse and Greenville?

Stops in Syracuse

A - Regional Transportation Center

B - Syracuse Airport

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Stops in Greenville

A - Guadalajara Supermarket Bus Stop

B - Greenville Bus Station

Frequently asked questions about travelling from Syracuse, US to Greenville, SC by bus

How much does a bus ticket from Syracuse to Greenville cost?
The bus ticket price from Syracuse to Greenville starts at R 1 844. The best way to find cheap bus tickets from Syracuse to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Syracuse to Greenville?
The average travel time between Syracuse and Greenville is around 22h 20m, although the fastest bus will take about 20h 55m. This is the time it takes to travel the 1060 km that separates the two cities.
How many daily bus connections are there between Syracuse and Greenville?
The number of buses from Syracuse to Greenville can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Syracuse to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Syracuse to Greenville?
When taking the bus from Syracuse to Greenville, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Syracuse to Greenville?
Buses travelling between Syracuse and Greenville leave from Regional Transportation Center or Syracuse Airport and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/11

R 3 314

13/11

R 2 051

Today

R 2 130

15/11

R 2 051

16/11

R 2 157

17/11

R 2 034

18/11

No data

19/11

R 1 990

The cheapest trip from Syracuse, US to Greenville, SC was searched and found on 19 Nov 2025 with a price of R 1 990

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Greenville, SC as early as possible.

You can expect to pay from R 1 990 to R 3 471 for a bus ticket from Syracuse, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 990, which is on 2025-11-19.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.