Find coaches from Tuscaloosa to Greenville, SC

Next departures

Next departures from Tuscaloosa to Greenville on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Tuscaloosa Greyhound Bus Station
1116 Woodruff RdCheapest
Greyhound Lines, Inc.
Tuscaloosa Greyhound Bus Station
1116 Woodruff RdFastest

Last refresh of the prices: Last Monday at 6:07 AM CDT.

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Compare 2 ways to travel from Tuscaloosa to Greenville

busbud logoWe recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 10 hours 9 minutes and with fares starting at just US$80, it presents an excellent value for a comfortable ride.

1train per day
10h 9mAverage duration
510 kmDistance
46kgCO₂ emissions
Bus
Average priceUS$40 - US$147Average duration11h 35m
13kg CO₂e
Train
Average priceUS$80 - US$119Average duration10h 9m
46kg CO₂e

Bus Tuscaloosa to Greenville, SC: Trip Overview

Average ticket priceUS$60
Average bus trip duration11h 35m
Number of daily buses2
Earliest bus departure06:45
Distance517 km
Latest bus departure20:50

Tuscaloosa to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Tuscaloosa to Greenville.

We make sure you can find a bus service from Tuscaloosa to Greenville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Tuscaloosa to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Tuscaloosa - Greenville, SC

  1. How much does a bus ticket from Tuscaloosa to Greenville cost?

    The bus ticket price from Tuscaloosa to Greenville starts at US$40. The best way to find cheap bus tickets from Tuscaloosa to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Tuscaloosa to Greenville?

    The average travel time between Tuscaloosa and Greenville is around 11h 35m, although the fastest bus will take about 9h 15m. This is the time it takes to travel the 514 km that separates the two cities.

  3. How many daily bus connections are there between Tuscaloosa and Greenville?

    The number of buses from Tuscaloosa to Greenville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Tuscaloosa to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Tuscaloosa to Greenville?

    When taking the bus from Tuscaloosa to Greenville, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
No data
30/10
US$32
Today
US$47
01/11
US$77
02/11
No data
03/11
No data
04/11
No data
05/11
No data
busbud logoThe cheapest trip from Tuscaloosa to Greenville, SC was searched and found on 30 Oct 2025 with a price of US$32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tuscaloosa to Greenville, SC as early as possible.

You can expect to pay from US$32 to US$77 for a bus ticket from Tuscaloosa to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$77, which is on 2025-11-01.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Tuscaloosa to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tuscaloosa to Greenville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tuscaloosa to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Tuscaloosa to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Tuscaloosa to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Tuscaloosa by bus?

Bus from Greenville, SC to Tuscaloosa

You can also go to Greenville, SC by train

Train from Tuscaloosa to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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