Find coaches from Wilmington, DE to St. Louis

Previously seen journeys

Next departures from Wilmington to St. Louis on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Wilmington Bus Station
Gateway StationNo tags
Greyhound
Wilmington Bus Station
Gateway StationNo tags
Greyhound
Wilmington Bus Station
Gateway StationNo tags
Greyhound
Wilmington Bus Station
Gateway StationNo tags
Greyhound
Wilmington Bus Station
Gateway StationNo tags

Accepted payments

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Compare 2 ways to travel from Wilmington to St. Louis

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 3 hours 55 minutes and with fares starting at just US$76, it presents an excellent value for a comfortable ride.

7bus per day
1d 3hAverage duration
1251 kmDistance
31kgCO₂ emissions
Bus
Average priceUS$76 - US$229Average duration1d 3h
31kg CO₂e
Train
Average priceUS$145 - US$527Average duration1d 11h
115kg CO₂e

Bus Wilmington, DE to St. Louis: Trip Overview

Average ticket priceUS$143
Average bus trip duration1d 3h
Number of daily buses7
Earliest bus departure02:50
Distance1250 km
Latest bus departure21:25

Wilmington to St. Louis Bus

Busbud helps you find a bus from Wilmington to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Wilmington to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Wilmington, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Wilmington, DE - St. Louis

  1. How much does a bus ticket from Wilmington to St. Louis cost?

    The bus ticket price from Wilmington to St. Louis starts at US$76. The best way to find cheap bus tickets from Wilmington to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Wilmington to St. Louis?

    The average travel time between Wilmington and St. Louis is around 1d 3h, although the fastest bus will take about 1d 2h. This is the time it takes to travel the 1269 km that separates the two cities.

  3. How many daily bus connections are there between Wilmington and St. Louis?

    The number of buses from Wilmington to St. Louis can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Wilmington to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Wilmington to St. Louis?

    When taking the bus from Wilmington to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Wilmington to St. Louis?

    Buses travelling between Wilmington and St. Louis leave from Wilmington Bus Station or Wilmington Station and arrive at Gateway Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
US$163
30/10
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busbud logoThe cheapest trip from Wilmington, DE to St. Louis was searched and found on 29 Oct 2025 with a price of US$163

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to St. Louis as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and St. Louis!

Much more than a mere vehicle taking you from Wilmington to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Wilmington, DE to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Wilmington, DE by bus?

Bus from St. Louis to Wilmington, DE

You can also go to St. Louis by train

Train from Wilmington, DE to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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