Find coaches from Wilmington, DE to St. Louis

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Today1 Sept
Tomorrow2 Sept
Wed3 Sept
from US$86
Thu4 Sept
Fri5 Sept
Sat6 Sept
Sun7 Sept
Mon8 Sept

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 3 September at
    Departure city: Wilmington
    Departure location: Delaware Rest Stop S
    Arrival time: 4 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 3 September at
    Departure city: Wilmington
    Departure location: Wilmington Bus Station
    Arrival time: 4 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Wilmington
    Departure location: Wilmington Bus Station
    Arrival time: 4 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Wilmington
    Departure location: Newark (DE)
    Arrival time: 4 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Wilmington
    Departure location: Newark (DE)
    Arrival time: 4 September at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Wilmington to St. Louis

Bus
Average priceUS$86 - US$187Average duration1d 4h
31kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$193 - US$1,025Average duration1d 11h
115kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Wilmington to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 4 hours 35 minutes and with fares starting at just US$86, it presents an excellent value for a comfortable ride.

7bus per day
1d 4hAverage duration
US$86Cheapest ticket
31kgCO₂ emissions

Bus Wilmington, DE to St. Louis: Trip Overview

Average ticket priceUS$114
Average bus trip duration1d 4h
Number of daily buses7
Earliest bus departure02:50
Distance779 miles
Latest bus departure21:25

Wilmington to St. Louis Bus

Busbud helps you find a bus from Wilmington to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Wilmington to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Wilmington, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Wilmington, DE - St. Louis

  1. What's the distance between Wilmington and St. Louis by coach?

    The distance between Wilmington and St. Louis by coach is approximately 787 miles (1269 km).

  2. How can I travel from Wilmington to St. Louis avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
No data
31/08
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Today
No data
02/09
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03/09
US$79
04/09
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05/09
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06/09
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busbud logoThe cheapest trip from Wilmington, DE to St. Louis was searched and found on 3 Sept 2025 with a price of US$79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to St. Louis as early as possible.

You can expect to pay from US$79 to US$122 for a bus ticket from Wilmington, DE to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$79, which is on 2025-09-03.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and St. Louis!

Much more than a mere vehicle taking you from Wilmington to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Wilmington, DE to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Wilmington, DE by bus?

Bus from St. Louis to Wilmington, DE

You can also go to St. Louis by train

Train from Wilmington, DE to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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