Train from Prague to Brussels: Tickets & Timetables

Next train departures

Next departures from Prague to Brussels on 24 May
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
European SleeperTrain
Hlavní nádraží
Brussels South/Midi Train StationCheapest
European SleeperTrain
Hlavní nádraží
Brussels South/Midi Train StationFastest
European SleeperTrain
Hlavní nádraží
Brussels South/Midi Train StationNo tags
European SleeperTrain
Hlavní nádraží
Brussels South/Midi Train StationNo tags
European SleeperTrain
Hlavní nádraží
Brussels South/Midi Train StationNo tags

Last refresh of the prices: Today at 12:30 AM CEST.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Brussels. The journey takes about 18 hours and with fares starting at just R 777, it presents an excellent value for a comfortable ride.

26bus per day
18hAverage duration
713 kmDistance
18kgCO₂ emissions
Average priceR 777 - R 4 488Average duration18h
18kg CO₂e
Average priceR 1 406 - R 5 409Average duration15h 27m
17kg CO₂e

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/05
R 5 384
22/05
No data
Today
No data
24/05
R 3 723
25/05
No data
26/05
R 3 306
27/05
No data
28/05
R 2 485
busbud logoThe cheapest trip from Prague to Brussels was searched and found on 28 May 2026 with a price of R 2 485

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Brussels as early as possible.

You can expect to pay from R 2 485 to R 19 648 for a train ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 485, which is on 2026-05-28.

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