Bus from Prague to Brussels: Tickets & Timetables

Next bus departures

Next departures from Prague to Brussels on 2 February
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
Prague (Central Bus Station Florenc)
Brussels North Train StationCheapestFastest
FlixbusBus
Prague (Central Bus Station Florenc)
Brussels AirportNo tags
FlixbusBus
Prague (Main Railway Station)
Brussels AirportNo tags
FlixbusBus
Prague (Main Railway Station)
Brussels AirportNo tags
FlixbusBus
Prague (Main Railway Station)
Brussels AirportNo tags

Last refresh of the prices: Today at 1:03 PM CET.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Brussels. The journey takes about 15 hours 27 minutes and with fares starting at just R 1 426, it presents an excellent value for a comfortable ride.

1train per day
15h 27mAverage duration
720 kmDistance
17kgCO₂ emissions
Average priceR 729 - R 4 057Average duration18h 25m
18kg CO₂e
Average priceR 1 426 - R 3 952Average duration15h 27m
17kg CO₂e

Frequently asked questions about travelling from Prague to Brussels by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Prague to Brussels?

    The cheapest bus tickets from Prague to Brussels start at R 729. The average price for this route is around R 1 304. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Prague to Brussels?

    The average bus journey time from Prague to Brussels is 18h 25m, covering a distance of 710 km. The fastest bus gets you there in 11h 30m and is operated by FlixBus.

  3. Which bus companies service the Prague to Brussels route?

    Several major bus companies operate on this route with 31 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.

  4. What is the earliest and latest departure time for the bus from Prague to Brussels?

    The earliest bus departs from Prague to Brussels at 00:10. And the latest bus departs at 23:05.

  5. What are the CO₂ emissions for the bus trip from Prague to Brussels?

    A bus trip from Prague to Brussels produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Prague to Brussels?

    According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1067 reviews.

  7. Which bus company has the best Wi-Fi from Prague to Brussels?

    Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

  8. Which bus company offers the most punctual service from Prague to Brussels?

    According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Prague to Brussels?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/01
R 1 152
31/01
R 947
Today
No data
02/02
R 1 084
03/02
R 1 010
04/02
No data
05/02
No data
06/02
R 801
busbud logoThe cheapest trip from Prague to Brussels was searched and found on 06 Feb 2026 with a price of R 801

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

You can expect to pay from R 801 to R 2 397 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 801, which is on 2026-02-06.

What's the cheapest way to go from Prague to Brussels?

busbud logoThe Bus is the cheapest travel choice for this destination

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