Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Brussels North Train Station | Wuppertal | Cheapest | ||||
| Bus
| Brussels North Train Station | Wuppertal | Fastest | ||||
| Bus
| Brussels North Train Station | Wuppertal | No tags |
Last refresh of the prices: Yesterday at 11:56 AM CEST.
Compare 2 ways to go from Brussels to Wuppertal
Among the sustainable travel choices, the Bus stands out as a good way to reach Wuppertal. The journey takes about 11 hours 10 minutes and with fares starting at just $23, it presents an excellent value for a comfortable ride.
Bus stations and stops in Brussels and Wuppertal
Stops in Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium - C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Stops in Wuppertal
- A
Wuppertal
Berliner Straße 206, 42277 Wuppertal - B
Wuppertal (Bf. Oberbarmen)
Paul-Humburg-Straße 5-6, 42275 Wuppertal, Germany - C
Döppersberg
Döppersberg 35A, 42103 Wuppertal, Germany
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Brussels to Wuppertal by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Wuppertal?
The cheapest bus tickets from Brussels to Wuppertal start from $23. The average price for this route is around $44. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Wuppertal?
The average bus trip duration from Brussels to Wuppertal is 11h 10m, covering a distance of 128 miles (206 km). The quickest bus can get you there in 10h 35m and is operated by FlixBus.
Which bus companies service the Brussels to Wuppertal route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Brussels to Wuppertal?
The earliest bus departs from Brussels to Wuppertal at 8:10am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Wuppertal?
A bus trip from Brussels to Wuppertal generates an estimated 5.134625 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Wuppertal was searched and found on Oct 19, 2026 with a price of $48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Wuppertal, as early as possible.
You can expect to pay from $48 to $93 for a bus ticket from Brussels to Wuppertal based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2026-10-24.
