Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | CheapestFastest | ||||
| Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags | ||||
| Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags | ||||
| Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags | ||||
| Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags | ||||
| Bus
| Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags |
Last refresh of the prices: Last Thursday at 12:52 AM CEST.
Compare 2 ways to go from Florence to Lyon
Among the sustainable travel choices, the Bus stands out as a good way to reach Lyon. The journey takes about 12 hours 30 minutes and with fares starting at just PEN 71, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Lyon
Stops in Florence
- A
Terminal Bus Villa Constanza
A1 - Autostrada del Sole, 50018 Scandicci FI, Italy - B
Florence - Piazzale Montelungo
50129 Centro Storico FI, Italy - D
Santa Maria Novella
Piazza della Stazione 45, 50123 Firenze, Italy - E
Via Cassia, 49B
Via Cassia, 49B, 50023 Impruneta FI, Italy - F
Scandicci - Villa Costanza
Via della Costituzione, 185, 50018 Scandicci FI, Italy
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
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Frequently asked questions about traveling from Florence to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Lyon?
The cheapest bus tickets from Florence to Lyon start from PEN 71. The average price for this route is around PEN 255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Lyon?
The average bus trip duration from Florence to Lyon is 12h 30m, covering a distance of 337 miles (544 km). The quickest bus can get you there in 10h 40m and is operated by FlixBus.
Which bus companies service the Florence to Lyon route?
Several major bus companies operate on this route with 5 buses available per day, including services from FlixBus, Itabus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Florence to Lyon?
The earliest bus departs from Florence to Lyon at 12:05am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Florence to Lyon?
A bus trip from Florence to Lyon generates an estimated 13.585849999999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Lyon?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1114 reviews.
Which bus company has the best Wi-Fi from Florence to Lyon?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.7.
Which bus company has the most timely service from Florence to Lyon?
According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Florence to Lyon?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence to Lyon was searched and found on Oct 8, 2026 with a price of PEN 62To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Lyon, as early as possible.
You can expect to pay from PEN 62 to PEN 508 for a bus ticket from Florence to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 62 which is on 2026-10-08.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
