Bus from Florence to Lyon: Tickets & Schedules

Next bus departures

Next departures for Florence to Lyon on December 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ItabusBus
Terminal Bus Villa Constanza
Lyon Lyon Perrache Bus StationCheapest
BlaBlaCar BusBus
    		Florence, Villa Costanza A1
    		Lyon - Perrache Bus StationFastest
    BlaBlaCar BusBus
      		Florence, Villa Costanza A1
      		Lyon - Perrache Bus StationNo tags
      ItabusBus
      		Terminal Bus Villa Constanza
      		Lyon Lyon Perrache Bus StationNo tags
      ItabusBus
      		Terminal Bus Villa Constanza
      		Lyon Lyon Perrache Bus StationNo tags

      Last refresh of the prices: Today at 4:12 AM CET.

      Compare 3 ways to go from Florence to Lyon

      We recommend carpooling

      Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 7 hours 40 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.

      1carpool per day
      7h 40mAverage Duration
      342 milesDistance
      23kgCO₂ emissions
      Bus
      		Average Price$22 - $181Average Duration12h 25m
      13kg CO₂e
      Train
      		Average Price$152 - $341Average Duration7h 37m
      13kg CO₂e
      Carpool
      		Average Price$49 - $79Average Duration7h 40m
      23kg CO₂e

      Frequently asked questions about traveling from Florence to Lyon by bus

      Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

      1. How much is the bus ticket from Florence to Lyon?

        The cheapest bus tickets from Florence to Lyon start from $22. The average price for this route is around $75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

      2. How long is the bus ride from Florence to Lyon?

        The average bus trip duration from Florence to Lyon is 12h 25m, covering a distance of 331 miles (533 km). The quickest bus can get you there in 10h 40m and is operated by FlixBus.

      3. Which bus companies service the Florence to Lyon route?

        Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Itabus, BlaBlaCar Bus, RegioJet.

      4. What is the earliest and latest departure time for the bus from Florence to Lyon?

        The earliest bus departs from Florence to Lyon at 12:05am. And the latest bus departs at 11:40pm.

      5. What are the CO₂ emissions for the bus trip from Florence to Lyon?

        A bus trip from Florence to Lyon generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

      6. What is the best bus company from Florence to Lyon?

        According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.

      7. Which bus company has the best Wi-Fi from Florence to Lyon?

        Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

      8. Which bus company has the most timely service from Florence to Lyon?

        According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.

      9. Which bus company has the cleanest buses from Florence to Lyon?

        According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      12/19
      $35
      12/20
      $64
      Today
      $35
      12/22
      $35
      12/23
      $49
      12/24
      $49
      12/25
      $60
      12/26
      $42
      busbud logoThe cheapest trip from Florence to Lyon was searched and found on Dec 19, 2025 with a price of $35

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Lyon, as early as possible.

      You can expect to pay from $35 to $118 for a bus ticket from Florence to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-12-22.

      Usually FlixBus, Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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