Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | Cheapest | ||||
 | Bus | Florence, Villa Costanza A1 | Lyon (Gerland) | Fastest | ||||
 | Bus | Scandicci - parcheggio scambiatore Villa Costanza | Lyon (Gerland) | No tags | ||||
| Bus | Terminal Bus Villa Constanza | Lyon Avenue Tony Garnier | No tags | ||||
| Bus | Florence, Villa Costanza A1 | Aéroport LYS | No tags |
Last refresh of the prices: Last Thursday at 6:08 PM CET.
Compare 3 ways to go from Florence to Lyon
Among the sustainable travel choices, the Bus stands out as a good way to reach Lyon. The journey takes about 12 hours 5 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Lyon?
Stops in Florence
- A
Florence - Piazzale Montelungo
50129 Centro Storico FI, Italy - CA1 - Autostrada del Sole, 50018 Scandicci FI, Italy
- DVia della Costituzione, 185, 50018 Scandicci FI, Italy
- EPiazza della Stazione 45, 50123 Firenze, Italy
- FVia Cassia, 49B, 50023 Impruneta FI, Italy
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about traveling from Florence to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Lyon?
The cheapest bus tickets from Florence to Lyon start from $24. The average price for this route is around $48. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Lyon?
The average bus trip duration from Florence to Lyon is 12h 5m, covering a distance of 340 miles (548 km). The quickest bus can get you there in 9h 55m and is operated by BlaBlaCar Bus.
Which bus companies service the Florence to Lyon route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Itabus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Florence to Lyon?
The earliest bus departs from Florence to Lyon at 12:05am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Florence to Lyon?
A bus trip from Florence to Lyon generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Lyon?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1069 reviews.
Which bus company has the best Wi-Fi from Florence to Lyon?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Florence to Lyon?
According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Lyon?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence to Lyon was searched and found on Feb 11, 2026 with a price of $36To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Lyon, as early as possible.
You can expect to pay from $36 to $157 for a bus ticket from Florence to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2026-02-11.
Usually RegioJet, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Florence to Lyon?
The Bus is the cheapest travel choice for this destination
