Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Frankfurt - Main bus station | Karlsruhe | Cheapest | |||||
 | Frankfurt Hbf | Südseite Hauptbahnhof | Fastest | |||||
| FRA Frankfurt airport | Südseite Hauptbahnhof | No tags | |||||
Flixbus + Flixtrain | FRA Frankfurt airport | Karlsruhe Hbf | No tags | |||||
| FRA Frankfurt airport | Südseite Hauptbahnhof | No tags |
Last refresh of the prices: Yesterday at 12:10 AM CET.
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Compare 3 ways to go from Frankfurt am Main to Karlsruhe
Among the sustainable travel choices, the carpool stands out as the good way to reach Karlsruhe. The journey takes about 1 hour 30 minutes and with fares starting at just $8, it presents an excellent value for a comfortable ride.
Bus Frankfurt am Main to Karlsruhe: Trip Overview
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Frankfurt am Main to Karlsruhe Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Frankfurt am Main to Karlsruhe.
We make sure you can find a bus service from Frankfurt am Main to Karlsruhe from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Frankfurt am Main to Karlsruhe, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Frankfurt am Main and Karlsruhe?
Frequently asked questions for your trip Frankfurt am Main - Karlsruhe
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Frankfurt am Main to Karlsruhe was searched and found on Nov 7, 2025 with a price of $8To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Karlsruhe, as early as possible.
You can expect to pay from $8 to $41 for a bus ticket from Frankfurt am Main to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $8 which is on 2025-11-07.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Frankfurt am Main to Karlsruhe but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Frankfurt am Main to Karlsruhe, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Frankfurt am Main to Karlsruhe that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Frankfurt am Main to Karlsruhe, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Popular Buses Connecting Frankfurt am Main
Buses Leaving from Frankfurt am Main
- Bus from Frankfurt am Main to Heidelberg
- Bus Frankfurt am Main - Pristina
- Frankfurt am Main - London
- Bus from Frankfurt am Main to Essen
- Bus Frankfurt am Main - Amsterdam
- Frankfurt am Main - Luxembourg
- Bus from Frankfurt am Main to Hahn
- Bus Frankfurt am Main - Cologne
- Frankfurt am Main - Munich
- Bus from Frankfurt am Main to Düsseldorf
- Bus Frankfurt am Main - Eisenach
- Frankfurt am Main - Stuttgart
- Bus from Frankfurt am Main to Hamburg
- Bus Frankfurt am Main - Mannheim
- Frankfurt am Main - Mainz
Buses Going to Frankfurt am Main
- Bus from Munich to Frankfurt am Main
- Bus Paris - Frankfurt am Main
- Tours - Frankfurt am Main
- Bus from Heidelberg to Frankfurt am Main
- Bus Pristina - Frankfurt am Main
- Strasbourg - Frankfurt am Main
- Bus from Hahn to Frankfurt am Main
- Bus Cologne - Frankfurt am Main
- Düsseldorf - Frankfurt am Main
- Bus from Nuremberg to Frankfurt am Main
- Bus Dortmund - Frankfurt am Main
- Bonn - Frankfurt am Main
- Bus from Karlsruhe to Frankfurt am Main
- Bus Dresden - Frankfurt am Main
- Koblenz - Frankfurt am Main
Popular Buses Connecting Karlsruhe
Buses Leaving from Karlsruhe
- Bus from Karlsruhe to Kaiserslautern
- Bus Karlsruhe - Regensburg
- Karlsruhe - Paris
- Bus from Karlsruhe to Stuttgart
- Bus Karlsruhe - Hamburg
- Karlsruhe - Paderborn
- Bus from Karlsruhe to Hanover
- Bus Karlsruhe - Frankfurt am Main
- Karlsruhe - Freiburg
- Bus from Karlsruhe to Heidelberg
- Bus Karlsruhe - Cologne
- Karlsruhe - Ulm
- Bus from Karlsruhe to Essen
- Bus Karlsruhe - Berlin
- Karlsruhe - Reutlingen
Buses Going to Karlsruhe
- Bus from Darmstadt to Karlsruhe
- Bus Paderborn - Karlsruhe
- Regensburg - Karlsruhe
- Bus from Mannheim to Karlsruhe
- Bus Berlin - Karlsruhe
- Wertheim - Karlsruhe
- Bus from Cologne to Karlsruhe
- Bus Heidelberg - Karlsruhe
- Stuttgart - Karlsruhe
- Bus from Frankfurt am Main to Karlsruhe
- Bus Schwangau - Karlsruhe
- Munich - Karlsruhe
- Bus from Nuremberg to Karlsruhe
- Bus Rosenheim - Karlsruhe
- Rust - Karlsruhe
Popular routes in this country
- Bus from Frankfurt am Main to Berlin
- Bus Stuttgart - Berlin
- Cologne - Berlin
- Bus from Berlin to Dresden
- Bus Munich - Berlin
- Cologne - Hamburg
- Bus from Hanover to Berlin
- Bus Berlin - Leipzig
- Dresden - Berlin
- Bus from Düsseldorf to Berlin
- Bus Leipzig - Berlin
- Berlin - Stuttgart
- Bus from Stuttgart to Frankfurt am Main
- Bus Hamburg - Cologne
- Düsseldorf - Hamburg