What is the distance between Lyon and Prague?

Lyon and Prague are 534 miles (861 km) apart.

What are the departure and arrival stations when taking the bus from Lyon to Prague?

If you're headed to Prague from Lyon, chances are that your bus will depart from Perrache and arrive at Zličín. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in Prague?

Once in Prague, you can start exploring the city and discover its surroundings. The top sights and things to do are Mind Maze, KGB Museum, Prague Castle and St. Vitus’ Cathedral, Karlův most (Charles Bridge) and Prague Shooting Trips.

Bus Lyon to Prague from $54 | Refundable Tickets

Next bus departures

Next departures for Lyon to Prague on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	12:00pm	Lyon - Perrache Bus Station	21h 45m	9:45am	Florenc	CheapestFastest

Last refresh of the prices: Yesterday at 7:12 AM CET.

Get from Lyon to Prague

This route is served by bus only

The journey takes about 19 hours 30 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

8bus per day

19h 30mAverage Duration

535 milesDistance

22kgCO₂ emissions

Where are the popular stops in Lyon and Prague?

Stops in Lyon

A
Perrache
Rue de Esplanade, 69002 Lyon, France
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B
Lyon Airport
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C
Lyon
8 Rue de la Paix, 69700 Givors, France
D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France
E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France
F
Les Charrières
Les Charrières, 69570 Dardilly, France
Visit page

Stops in Prague

A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
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C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
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D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
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E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare bus companies

FlixBus

3.5/511,388 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

BlaBlaCar Bus

3.5/511,143 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

RegioJet

4/51,057 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

CZ bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Lyon to Prague by bus

What is the distance between Lyon and Prague?
What are the departure and arrival stations when taking the bus from Lyon to Prague?
What are the best sights and things to do in Prague?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/19

No data

11/20

No data

Today

$113

11/22

$60

11/23

No data

11/24

$85

11/25

No data

11/26

No data

The cheapest trip from Lyon to Prague was searched and found on Nov 22, 2025 with a price of $60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.

You can expect to pay from $60 to $113 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2025-11-22.