Bus Tickets from Milano to Prague

Find affordable bus tickets from Milano to Prague with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 20
from $108
TomorrowJul 21
from $92
TueJul 22
from $96
WedJul 23
ThuJul 24
from $71
FriJul 25
from $88
SatJul 26
from $90
SunJul 27

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 21 at
    Departure city: Milano
    Departure location: Aeroporto Linate Airport (LIN)
    Arrival time: July 22 at
    Destination city: Prague
    Destination location: Prague (Main Railway Station)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 21 at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: July 22 at
    Destination city: Prague
    Destination location: Prague (Main Railway Station)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: July 21 at
    Departure city: Milano
    Departure location: Aeroporto Linate Airport (LIN)
    Arrival time: July 22 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: July 21 at
    Departure city: Milano
    Departure location: Lampugnano
    Arrival time: July 21 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: July 21 at
    Departure city: Milano
    Departure location: Aeroporto Linate Airport (LIN)
    Arrival time: July 22 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Milano to Prague.

Bus
Average Price$50 - $285Average Duration18h 5m
16kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average Price$45 - $45Average Duration10h
27kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Milano to Prague

Among the sustainable travel choices, the bus stands out as the good way to reach Prague. The journey takes about 18 hours 5 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.

51bus per day
18h 5mAverage Duration
$50Cheapest ticket
16kgCO₂ emissions

Bus Milano to Prague: Trip Overview

Average ticket price$92
Average bus trip duration18h 5m
Number of daily buses51
Earliest bus departure1:15am
Distance399 miles (642 km)
Latest bus departure11:55pm

Milano to Prague Bus

Busbud helps you find a bus from Milano to Prague. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Milano to Prague will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Prague from Milano, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Milano - Prague

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/18
$92
07/19
$98
Today
$103
07/21
$88
07/22
$90
07/23
$72
07/24
$67
07/25
$84
busbud logoThe cheapest trip from Milano to Prague was searched and found on Jul 24, 2025 with a price of $67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Prague, as early as possible.

You can expect to pay from $67 to $216 for a bus ticket from Milano to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-07-24.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Prague!

Much more than a mere vehicle taking you from Milano to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Milano to Prague.

Tune out to the fine sounds of your best music playlist on your bus trip from Milano to Prague while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Milano by bus?

Bus from Milano to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Milano

Buses Leaving from Milano

Buses Going to Milano

Popular Buses Connecting Prague

Buses Leaving from Prague

Buses Going to Prague