Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Metropark Centrale | Isernia | CheapestFastest |
Last refresh of the prices: Yesterday at 8:48 PM CEST.
Get from Naples to Isernia
The journey takes about 2 hours 9 minutes and with fares starting at just CHF 11, it presents an excellent value for a comfortable ride.
Bus stations and stops in Naples and Isernia
Stops in Naples
- A
Garibaldi
Corso Arnaldo Lucci 195, 80142 Napoli, Italy - C
Stazione Marittima
Piazzale Stazione Marittima, 80133 Napoli NA, Italy - D
Pisacane
Pisacane, 80133 Napoli NA, Italy - E
Immacolatella Vecchia
Calata Porta di Massa, 80133 Napoli, Italy - F
Via Benedetto Brin
Via Benedetto Brin, 3A, 80142 Napoli NA, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Naples to Isernia by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Naples to Isernia?
The cheapest bus tickets from Naples to Isernia start from CHF 11. The average price for this route is around CHF 13. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Naples to Isernia?
The average bus trip duration from Naples to Isernia is 2h 9m, covering a distance of 52 miles (84 km). The quickest bus can get you there in 1h 59m and is operated by FlixBus.
Which bus companies service the Naples to Isernia route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Naples to Isernia?
The earliest bus departs from Naples to Isernia at 9:35am. And the latest bus departs at 9:35am.
What are the CO₂ emissions for the bus trip from Naples to Isernia?
A bus trip from Naples to Isernia generates an estimated 2.076975 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Naples to Isernia was searched and found on Sep 10, 2026 with a price of CHF 10To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Naples to Isernia, as early as possible.
You can expect to pay from CHF 10 to CHF 19 for a bus ticket from Naples to Isernia based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 10 which is on 2026-09-13.
