Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Lampugnano | Cheapest | ||||
| Bus | Terminal Bus Palermo | Milan San Donato Bus Station | Fastest |
Last refresh of the prices: Yesterday at 12:42 AM CEST.
Get from Palermo to Milano
The journey takes about 1 day, 1 hour 10 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.
Where are the popular stops in Palermo and Milano?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- E
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy - F
Piazza Ruggero Settimo, 12
Piazza Ruggero Settimo, 12C, 90139 Palermo, Italy
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- BVia Giuseppe Impastato, 27, 20138 Milano, Italy
- DPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
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Frequently asked questions about traveling from Palermo to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Palermo to Milano?
The cheapest bus tickets from Palermo to Milano start from $76. The average price for this route is around $120. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Palermo to Milano?
The average bus trip duration from Palermo to Milano is 1d 1h, covering a distance of 557 miles (898 km). The quickest bus can get you there in 19h 10m and is operated by Autoservizi Salemi.
Which bus companies service the Palermo to Milano route?
Several major bus companies operate on this route with 9 buses available per day, including services from FlixBus, Autoservizi Salemi, Itabus.
What is the earliest and latest departure time for the bus from Palermo to Milano?
The earliest bus departs from Palermo to Milano at 9:10am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Palermo to Milano?
A bus trip from Palermo to Milano generates an estimated 22.4268 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Palermo to Milano?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 503 reviews.
Which bus company has the best Wi-Fi from Palermo to Milano?
Based on reviews on Busbud, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 4.0.
Which bus company has the most timely service from Palermo to Milano?
According to Busbud traveler reviews, the most timely bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Palermo to Milano?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Milano was searched and found on Jun 7, 2026 with a price of $80To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Milano, as early as possible.
You can expect to pay from $80 to $177 for a bus ticket from Palermo to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2026-06-07.
