Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus | Černý Most | Terminal Interbus | ||||
| Bus | Tomíčkova | Terminal Interbus | ||||
| Bus | Prague (Main Railway Station) | Terminal Interbus | ||||
| Bus | Prague (Na Knížecí) | Terminal Interbus | ||||
| Bus | Prague Hradčanská | Terminal Interbus |
Get from Prague to Syracuse
The journey takes about 1 day, 21 hours 55 minutes and with fares starting at just CZK 3,031, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Syracuse?
Stops in Prague
- A
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - B
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Syracuse
- A
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy - B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Prague to Syracuse by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Syracuse?
The cheapest bus tickets from Prague to Syracuse start from CZK 3,031. The average price for this route is around CZK 3,337. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Syracuse?
The average bus trip duration from Prague to Syracuse is 1d 21h, covering a distance of 899 miles (1450 km). The quickest bus can get you there in 1d 13h and is operated by FlixBus.
Which bus companies service the Prague to Syracuse route?
Several major bus companies operate on this route with 10 buses available per day.
What is the earliest and latest departure time for the bus from Prague to Syracuse?
The earliest bus departs from Prague to Syracuse at 7:20am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Syracuse?
A bus trip from Prague to Syracuse generates an estimated 36.226150000000004 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Syracuse was searched and found on Jun 17, 2026 with a price of CZK 2,952To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Syracuse, as early as possible.
