Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Siena Train Station | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Siena Train Station | Rome Tiburtina Bus Station | Fastest | ||||
 | Bus | Siena Train Station | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Siena Train Station | Rome Tiburtina Bus Station | No tags | ||||
 | Bus | Piazza Gramsci | Rome Fiumicino Airport (T3) | No tags | ||||
| Bus | Siena Train Station | Aeroporto Ciampino Airport (CIA) | No tags | ||||
 | Bus | Siena Train Station | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Siena Train Station | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Today at 8:21 AM CEST.
Compare 2 ways to go from Siena to Rome
Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 3 hours 5 minutes and with fares starting at just ARS 10,602, it presents an excellent value for a comfortable ride.
Bus stations and stops in Siena and Rome
Stops in Siena
- A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy - B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Stops in Rome
- A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about traveling from Siena to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Siena to Rome?
The cheapest bus tickets from Siena to Rome start from ARS 10,602. The average price for this route is around ARS 30,540. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Siena to Rome?
The average bus trip duration from Siena to Rome is 3h 5m, covering a distance of 116 miles (187 km). The quickest bus can get you there in 2h 40m and is operated by FlixBus.
Which bus companies service the Siena to Rome route?
Several major bus companies operate on this route with 30 buses available per day, including services from FlixBus, Itabus, Tiemme SpA, BusItalia, MarinoBus.
What is the earliest and latest departure time for the bus from Siena to Rome?
The earliest bus departs from Siena to Rome at 5:15am. And the latest bus departs at 10:25pm.
What are the CO₂ emissions for the bus trip from Siena to Rome?
A bus trip from Siena to Rome generates an estimated 4.669225 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Siena to Rome?
According to Busbud customers, the highest-rated bus company on this route is Tiemme SpA, with an average rating of 4.4 out of 5 stars based on 110 reviews.
Which bus company has the best Wi-Fi from Siena to Rome?
Based on reviews on Busbud, the bus company BusItalia has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Siena to Rome?
According to Busbud traveler reviews, the most timely bus company on this route is Tiemme SpA, with a punctuality rating of 4.5 out of 5 stars.
Which bus company has the cleanest buses from Siena to Rome?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Tiemme SpA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Siena to Rome was searched and found on Jul 31, 2026 with a price of ARS 8,881To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Rome, as early as possible.
You can expect to pay from ARS 8,881 to ARS 137,055 for a bus ticket from Siena to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 8,881 which is on 2026-07-31.
Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Siena to Rome?
The Bus is the cheapest travel choice for this destination
