Bus from Siena to Rome: Tickets & Schedules

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Next bus departures

Next departures for Siena to Rome on September 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ItabusBus
  • Wifi
  • Toilet
  • Power outlets
Siena Train Station
Rome Tiburtina Bus StationCheapest
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Siena Train Station
Rome Tiburtina Bus StationFastest
MarinoBusBus
  • Toilet
Siena Train Station
Rome Tiburtina Bus StationNo tags
ItabusBus
  • Wifi
  • Toilet
  • Power outlets
Siena Train Station
Rome Tiburtina Bus StationNo tags
TiemmeBus
Piazza Gramsci
Rome Fiumicino Airport (T3)No tags
Flixbus Bus
  • Wifi
  • Toilet
  • Power outlets
Siena Train Station
Aeroporto Ciampino Airport (CIA)No tags
BusitaliaBus
  • Toilet
  • Power outlets
Siena Train Station
Rome Tiburtina Bus StationNo tags
MarinoBusBus
  • Toilet
Siena Train Station
Rome Tiburtina Bus StationNo tags

Last refresh of the prices: Today at 6:24 AM CEST.

Compare 2 ways to go from Siena to Rome

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 3 hours and with fares starting at just CZK 159, it presents an excellent value for a comfortable ride.

32bus per day
3hAverage Duration
116 milesDistance
5kgCO₂ emissions
Average PriceCZK 159 - CZK 2,113Average Duration3h
5kg CO₂e
Average PriceCZK 648 - CZK 706Average Duration3h 52m
4kg CO₂e

Frequently asked questions about traveling from Siena to Rome by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Siena to Rome?

    The cheapest bus tickets from Siena to Rome start from CZK 159. The average price for this route is around CZK 327. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Siena to Rome?

    The average bus trip duration from Siena to Rome is 3h, covering a distance of 116 miles (187 km). The quickest bus can get you there in 2h 40m and is operated by FlixBus.

  3. Which bus companies service the Siena to Rome route?

    Several major bus companies operate on this route with 32 buses available per day, including services from FlixBus, Itabus, Tiemme SpA, BusItalia, MarinoBus.

  4. What is the earliest and latest departure time for the bus from Siena to Rome?

    The earliest bus departs from Siena to Rome at 4:15am. And the latest bus departs at 10:25pm.

  5. What are the CO₂ emissions for the bus trip from Siena to Rome?

    A bus trip from Siena to Rome generates an estimated 4.6658 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Siena to Rome?

    According to Busbud customers, the highest-rated bus company on this route is Tiemme SpA, with an average rating of 4.4 out of 5 stars based on 125 reviews.

  7. Which bus company has the best Wi-Fi from Siena to Rome?

    Based on reviews on Busbud, the bus company BusItalia has the best Wi-Fi rating with a score of 3.9.

  8. Which bus company has the most timely service from Siena to Rome?

    According to Busbud traveler reviews, the most timely bus company on this route is Tiemme SpA, with a punctuality rating of 4.5 out of 5 stars.

  9. Which bus company has the cleanest buses from Siena to Rome?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Tiemme SpA, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/18
CZK 102
09/19
CZK 128
Today
CZK 102
09/21
CZK 179
09/22
CZK 154
09/23
CZK 179
09/24
CZK 192
09/25
CZK 205
busbud logoThe cheapest trip from Siena to Rome was searched and found on Sep 18, 2026 with a price of CZK 102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Rome, as early as possible.

You can expect to pay from CZK 102 to CZK 1,685 for a bus ticket from Siena to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 154 which is on 2026-09-22.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Siena to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

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