How much is the train ticket from Jacksonville to Greenville?

The cheapest train tickets from Jacksonville to Greenville start from $133. The average price for this train route is around $276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Jacksonville to Greenville?

The average train ride duration from Jacksonville to Greenville is 1d 6h, covering a distance of 313 miles (504 km). The quickest train can get you there in 1d 6h and is operated by Amtrak .

Which train operators service the Jacksonville to Greenville route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Jacksonville to Greenville?

The earliest train departs from Jacksonville to Greenville at 4:11pm. And the latest train departs at 10:33pm.

Train Jacksonville to Greenville from $166 | Refundable Tickets

Previously seen trips

Next departures for Jacksonville to Greenville on January 17
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	5:11pm	Jacksonville Amtrak Station	1d 12h	5:24am	Greenville Station	No tags
Train	10:29pm	Jacksonville Amtrak Station	1d 6h	5:24am	Greenville Station	No tags
Train	5:11pm	Jacksonville Amtrak Station	1d 12h	5:24am	Greenville Station	No tags
Train	10:29pm	Jacksonville Amtrak Station	1d 6h	5:24am	Greenville Station	No tags
Train	5:11pm	Jacksonville Amtrak Station	1d 12h	5:24am	Greenville Station	No tags

Compare 2 ways to go from Jacksonville to Greenville

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach Greenville. The journey takes about 11 hours 15 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.

2bus per day

11h 15mAverage Duration

313 milesDistance

13kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$68 - $215	Average Duration11h 15m	CO₂ emissions 13kg CO₂e
Train	Average Price$133 - $1,337	Average Duration1d 6h	CO₂ emissions 46kg CO₂e

Train Companies

Amtrak

4/55,739 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5739 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $133

US train companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Jacksonville, FL to Greenville, SC by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Jacksonville to Greenville?
The cheapest train tickets from Jacksonville to Greenville start from $133. The average price for this train route is around $276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Jacksonville to Greenville?
The average train ride duration from Jacksonville to Greenville is 1d 6h, covering a distance of 313 miles (504 km). The quickest train can get you there in 1d 6h and is operated by Amtrak.
Which train operators service the Jacksonville to Greenville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Jacksonville to Greenville?
The earliest train departs from Jacksonville to Greenville at 4:11pm. And the latest train departs at 10:33pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/14

$166

01/15

$166

Today

$166

01/17

$166

01/18

No data

01/19

No data

01/20

No data

01/21

No data

The cheapest trip from Jacksonville, FL to Greenville, SC was searched and found on Jan 14, 2026 with a price of $166

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to Greenville, SC, as early as possible.

You can expect to pay from $166 to $1,294 for a train ticket from Jacksonville, FL to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $166 which is on 2026-01-17.