How much is the train ticket from Jacksonville to St. Louis?

The cheapest train tickets from Jacksonville to St. Louis start from $218. The average price for this train route is around $447. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Jacksonville to St. Louis?

The average train ride duration from Jacksonville to St. Louis is 2d , covering a distance of 746 miles (1202 km). The quickest train can get you there in 1d 21h and is operated by Amtrak .

Which train operators service the Jacksonville to St. Louis route?

Several major train operators operate on this route with 3 trains available per day.

What is the earliest and latest departure time for the train from Jacksonville to St. Louis?

The earliest train departs from Jacksonville to St. Louis at 4:11pm. And the latest train departs at 10:33pm.

Train Jacksonville to St. Louis from $209 | Refundable Tickets

Next train departures

Next departures for Jacksonville to St. Louis on January 10
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	Cheapest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	Fastest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags

Next departures for Jacksonville to St. Louis on January 11
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	Cheapest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	Fastest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags

Next departures for Jacksonville to St. Louis on January 14
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:33pm	Jacksonville Amtrak Station	2d 2h	12:09am	Gateway Station	Cheapest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	Fastest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags

Next departures for Jacksonville to St. Louis on January 16
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	10:33pm	Jacksonville Amtrak Station	2d 2h	12:09am	Gateway Station	Cheapest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	Fastest
Train	10:33pm	Jacksonville Amtrak Station	1d 21h	7:25pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags
Train	10:33pm	Jacksonville Amtrak Station	2d	10:23pm	Gateway Station	No tags

Last refresh of the prices: Last Sunday at 10:47 PM EST.

Compare 2 ways to go from Jacksonville to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach St. Louis. The journey takes about 1 day, 40 minutes and with fares starting at just $137, it presents an excellent value for a comfortable ride.

3bus per day

1d Average Duration

749 milesDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$137 - $300	Average Duration1d	CO₂ emissions 30kg CO₂e
Train	Average Price$218 - $2,836	Average Duration2d	CO₂ emissions 109kg CO₂e

Where are the popular train stations and stops in Jacksonville, FL and St. Louis?

Jacksonville, FL

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page Map

St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page Map

Train Companies

Amtrak

4/55,724 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5724 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $218

US train companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Jacksonville, FL to St. Louis by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Jacksonville to St. Louis?
The cheapest train tickets from Jacksonville to St. Louis start from $218. The average price for this train route is around $447. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Jacksonville to St. Louis?
The average train ride duration from Jacksonville to St. Louis is 2d , covering a distance of 746 miles (1202 km). The quickest train can get you there in 1d 21h and is operated by Amtrak.
Which train operators service the Jacksonville to St. Louis route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the train from Jacksonville to St. Louis?
The earliest train departs from Jacksonville to St. Louis at 4:11pm. And the latest train departs at 10:33pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/08

$264

01/09

$310

Today

$249

01/11

$256

01/12

$209

01/13

No data

01/14

$216

01/15

No data

The cheapest trip from Jacksonville, FL to St. Louis was searched and found on Jan 12, 2026 with a price of $209

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to St. Louis, as early as possible.

You can expect to pay from $209 to $3,086 for a train ticket from Jacksonville, FL to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $209 which is on 2026-01-12.