How much is the bus ticket from Jacksonville to St. Louis?

The cheapest bus tickets from Jacksonville to St. Louis start from CZK 2,044. The average price for this route is around CZK 4,255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Jacksonville to St. Louis?

The average bus trip duration from Jacksonville to St. Louis is 19h 30m, covering a distance of 749 miles (1208 km). The quickest bus can get you there in 18h 5m and is operated by FlixBus .

Which bus companies service the Jacksonville to St. Louis route?

Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Jacksonville to St. Louis?

The earliest bus departs from Jacksonville to St. Louis at 9:30am. And the latest bus departs at 11:15pm.

What are the CO₂ emissions for the bus trip from Jacksonville to St. Louis?

A bus trip from Jacksonville to St. Louis generates an estimated 30.199450000000002 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Jacksonville to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 12448 reviews.

Which bus company has the best Wi-Fi from Jacksonville to St. Louis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Jacksonville to St. Louis?

According to Busbud traveler reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Jacksonville to St. Louis?

According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Jacksonville to St. Louis from CZK 2,157 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to St. Louis on April 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	19h 30m	3:55pm	Gateway Station	Cheapest
	Bus	4:30pm	Jacksonville Bus Station	18h 5m	9:35am	Gateway Station	Fastest

Last refresh of the prices: Yesterday at 4:28 PM EDT.

Compare 2 ways to go from Jacksonville to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 19 hours 30 minutes and with fares starting at just CZK 2,044, it presents an excellent value for a comfortable ride.

2bus per day

19h 30mAverage Duration

749 milesDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCZK 2,044 - CZK 5,788	Average Duration19h 30m	CO₂ emissions 30kg CO₂e
Train	Average PriceCZK 3,901 - CZK 63,115	Average Duration2d	CO₂ emissions 109kg CO₂e

Where are the popular stops in Jacksonville and St. Louis?

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

FlixBus

3.5/512,491 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,539 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Los Limousines

Frequently asked questions about traveling from Jacksonville, FL to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to St. Louis?
The cheapest bus tickets from Jacksonville to St. Louis start from CZK 2,044. The average price for this route is around CZK 4,255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to St. Louis?
The average bus trip duration from Jacksonville to St. Louis is 19h 30m, covering a distance of 749 miles (1208 km). The quickest bus can get you there in 18h 5m and is operated by FlixBus.
Which bus companies service the Jacksonville to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Jacksonville to St. Louis?
The earliest bus departs from Jacksonville to St. Louis at 9:30am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to St. Louis?
A bus trip from Jacksonville to St. Louis generates an estimated 30.199450000000002 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Jacksonville to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12448 reviews.
Which bus company has the best Wi-Fi from Jacksonville to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Jacksonville to St. Louis?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to St. Louis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

04/16

CZK 4,103

04/17

CZK 4,357

Today

CZK 4,780

04/19

No data

04/20

No data

04/21

No data

04/22

CZK 2,411

04/23

No data

The cheapest trip from Jacksonville, FL to St. Louis was searched and found on Apr 22, 2026 with a price of CZK 2,411

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to St. Louis, as early as possible.

You can expect to pay from CZK 2,411 to CZK 4,780 for a bus ticket from Jacksonville, FL to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 2,411 which is on 2026-04-22.