Next available departures

Next departures for Pisa to Rome on September 5
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:40am	Parcheggio Via Pietransantina	6h 25m	4:05pm	Rome Tiburtina Bus Station	Cheapest
5:13pm	Piazza della Stazione, 10	2h 47m	8:00pm	Termini	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
5:13pm	Piazza della Stazione, 10	2h 47m	8:00pm	Termini	No tags
7:15am	Parcheggio Via Pietransantina	6h 5m	1:20pm	Rome Tiburtina Bus Station	No tags
12:00pm	Parcheggio Via Pietransantina	5h 25m	5:25pm	Rome Tiburtina Bus Station	No tags
1:25pm	Parcheggio Via Pietransantina	5h 10m	6:35pm	Rome Tiburtina Bus Station	No tags
5:25pm	Parcheggio Via Pietransantina	5h 10m	10:35pm	Rome Tiburtina Bus Station	No tags

Next departures for Pisa to Rome on September 6
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:33am	Piazza della Stazione, 10	2h 37m	10:10am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:33am	Piazza della Stazione, 10	2h 37m	10:10am	Termini	No tags
7:15am	Parcheggio Via Pietransantina	6h 5m	1:20pm	Rome Tiburtina Bus Station	No tags
7:38am	Piazza della Stazione, 10	5h 27m	1:05pm	Termini	No tags

Next departures for Pisa to Rome on September 7
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
12:00pm	Parcheggio Via Pietransantina	5h 50m	5:50pm	Rome Anagnina	Cheapest
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	No tags
3:40pm	Piazza della Stazione, 10	4h 8m	7:48pm	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
5:07pm	Piazza della Stazione, 10	2h 56m	8:03pm	Termini	No tags

Next departures for Pisa to Rome on September 8
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
4:45am	Parcheggio Via Pietransantina	5h 30m	10:15am	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags

Next departures for Pisa to Rome on September 9
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:15am	Parcheggio Via Pietransantina	6h 5m	1:20pm	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
5:10pm	Parcheggio Via Pietransantina	5h 50m	11:00pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags

Next departures for Pisa to Rome on September 10
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:40am	Parcheggio Via Pietransantina	6h 25m	4:05pm	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags

Next departures for Pisa to Rome on September 11
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
4:45am	Parcheggio Via Pietransantina	5h 30m	10:15am	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:07am	Piazza della Stazione, 10	2h 56m	10:03am	Termini	No tags

Next departures for Pisa to Rome on September 12
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:40am	Parcheggio Via Pietransantina	6h 25m	4:05pm	Rome Tiburtina Bus Station	Cheapest
7:33am	Piazza della Stazione, 10	2h 13m	9:46am	Tiburtina	Fastest
8:20am	Fermata dell'autobus Pisa	6h	2:20pm	Rome Tiburtina Bus Station	No tags
7:33am	Piazza della Stazione, 10	2h 37m	10:10am	Termini	No tags
6:05am	park Aurelia	4h 45m	10:50am	Rome Tiburtina Bus Station	No tags
7:33am	Piazza della Stazione, 10	2h 37m	10:10am	Termini	No tags
12:25am	Parcheggio Via Pietransantina	5h 30m	5:55am	Rome Tiburtina Bus Station	No tags
7:33am	Piazza della Stazione, 10	2h 37m	10:10am	Termini	No tags

Last refresh of the prices: Today at 6:15 AM CEST.

Compare 2 ways to go from Pisa to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 46 minutes and with fares starting at just CHF 19, it presents an excellent value for a comfortable ride.

11train per day

3h 46mAverage Duration

165 milesDistance

6kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCHF 15 - CHF 145	Average Duration5h 50m	CO₂ emissions 7kg CO₂e
Train	Average PriceCHF 19 - CHF 169	Average Duration3h 46m	CO₂ emissions 6kg CO₂e

Bus stations and stops in Pisa and Rome

Stops in Pisa

A
Piazza della Stazione, 10
Piazza della Stazione, 10, 56125 Pisa PI, Italy
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B
Pisa Airport
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C
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI
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D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy
E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy
F
San Rossore
56122 Pisa PI, Italy

Stops in Rome

A
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
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B
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
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C
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
D
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
E
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
F
Rome Ciampino Airport
Visit page

Compare companies

FlixBus

3.5/515,509 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Trenitalia

3.9/569 reviews

Staff4.5

Timeliness4.4

Cleanliness4.7

Wifi2.7

MarinoBus

4.1/5976 reviews

Staff4.7

Timeliness4.3

Cleanliness4.5

Wifi3.5

BusItalia

4.0/5177 reviews

Staff4.9

Timeliness3.1

Cleanliness4.7

Wifi3.9

Itabus

3.8/51,064 reviews

Staff4.3

Timeliness3.0

Cleanliness4.1

Wifi2.8

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, NS Nederlandse Spoorwegen, Deutsche Bahn, Deutsche Bahn Regio, Sindbad, Deutsche Bahn ICE

Frequently asked questions about traveling from Pisa to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Pisa to Rome?
The cheapest tickets from Pisa to Rome start from CHF 15. The average price for this route is around CHF 28. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Pisa to Rome?
The average trip duration from Pisa to Rome is 4h 48m, covering a distance of 166 miles (267 km). The quickest vehicle can get you there in 2h 9m and is operated by Trenitalia.
Which companies service the Pisa to Rome route?
Several major companies operate on this route with 12 trips available per day, including services from FlixBus, MarinoBus, BusItalia, Itabus, Trenitalia.
What is the earliest and latest departure time from Pisa to Rome?
The earliest trip departs from Pisa to Rome at 12:25am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Pisa to Rome?
A trip from Pisa to Rome generates an estimated 6.665425 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Pisa to Rome?
According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 976 reviews.
Which company has the best Wi-Fi from Pisa to Rome?
Based on reviews on Busbud, the company BusItalia has the best Wi-Fi rating with a score of 3.9.
Which company has the most timely service from Pisa to Rome?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Rome?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/03

CHF 15

09/04

CHF 28

Today

CHF 18

09/06

CHF 18

09/07

CHF 15

09/08

CHF 13

09/09

CHF 13

09/10

CHF 12

The cheapest trip from Pisa to Rome was searched and found on Sep 10, 2026 with a price of CHF 12

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.

You can expect to pay from CHF 12 to CHF 121 for a bus or train ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 12 which is on 2026-09-10.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Pisa to Rome?

The Bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time5h 50m	Avg PriceCHF 25	Daily Departures13
Vehicle TypeTrain	Travel Time3h 46m	Avg PriceCHF 31	Daily Departures11
Vehicle TypeCarpool	Travel Time4h	Avg PriceCHF 28	Daily Departures10