How much is the train ticket from San Diego to Buffalo?

The cheapest train tickets from San Diego to Buffalo start from $610. The average price for this train route is around $610. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from San Diego to Buffalo?

The average train ride duration from San Diego to Buffalo is 2d 15h, covering a distance of 2187 miles (3528 km). The quickest train can get you there in 2d 15h and is operated by Amtrak .

Which train operators service the San Diego to Buffalo route?

Several major train operators operate on this route with 2 trains available per day.

What is the earliest and latest departure time for the train from San Diego to Buffalo?

The earliest train departs from San Diego to Buffalo at 2:01pm. And the latest train departs at 2:10pm.

Train San Diego to Buffalo from $1,868 | Refundable Tickets

Next departures

Next departures for San Diego to Buffalo on December 21
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
2:01pm	Santa Fe Depot	2d 15h	8:53am	Depew Station	Cheapest
2:10pm	Old Town San Diego	2d 15h	8:53am	Depew Station	Fastest
4:01pm	Santa Fe Depot	3d 13h	8:53am	Depew Station	No tags
4:10pm	Old Town San Diego	3d 13h	8:53am	Depew Station	No tags

Last refresh of the prices: Yesterday at 10:22 PM PST.

Compare 2 ways to go from San Diego to Buffalo

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 2 days, 15 hours 43 minutes and with fares starting at just $610, it presents an excellent value for a comfortable ride.

2train per day

2d 15hAverage Duration

2187 milesDistance

321kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$225 - $338	Average Duration3d 7h	CO₂ emissions 88kg CO₂e
Train	Average Price$610 - $610	Average Duration2d 15h	CO₂ emissions 321kg CO₂e

Train Companies

Amtrak

4/55,662 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5662 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $610

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from San Diego, CA, US to Buffalo, NY by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from San Diego to Buffalo?
The cheapest train tickets from San Diego to Buffalo start from $610. The average price for this train route is around $610. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from San Diego to Buffalo?
The average train ride duration from San Diego to Buffalo is 2d 15h, covering a distance of 2187 miles (3528 km). The quickest train can get you there in 2d 15h and is operated by Amtrak.
Which train operators service the San Diego to Buffalo route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from San Diego to Buffalo?
The earliest train departs from San Diego to Buffalo at 2:01pm. And the latest train departs at 2:10pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/18

No data

12/19

$527

Today

No data

12/21

$1,868

12/22

No data

12/23

No data

12/24

No data

12/25

No data

The cheapest trip from San Diego, CA, US to Buffalo, NY was searched and found on Dec 19, 2025 with a price of $527

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego, CA, US to Buffalo, NY, as early as possible.

You can expect to pay from $527 to $2,658 for a train ticket from San Diego, CA, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $1,868 which is on 2025-12-21.