How much does a train ticket from Detroit to St. Louis cost?

The average train ticket price from Detroit to St. Louis is $129. The best way to find train tickets from Detroit to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the train trip from Detroit to St. Louis?

A train trip between Detroit and St. Louis is around 13h 41m, although the fastest train will take about 13h 41m. This is the time it takes to travel the 454 miles that separates the two cities.

How many daily trains are there between Detroit and St. Louis?

The number of trains from Detroit to St. Louis can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Detroit to St. Louis by comparing and selecting the train that fits you travel style and budget on Busbud.

Which train companies travel from Detroit to St. Louis?

When taking the train from Detroit to St. Louis, you can travel comfortably and safely with Amtrak.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can explore the city. The top sights and things to do are Anheuser-Busch Brewery, Forest Park, Old St. Louis County Courthouse, Saint Louis Zoo, Gateway Arch.

Train Detroit to St. Louis from $71 | Refundable Tickets

Next train departures

Next departures for Detroit to St. Louis on November 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	Cheapest
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	Fastest
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	Cheapest
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	Fastest
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	No tags
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	No tags
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	CheapestFastest
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	No tags
Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	No tags
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	No tags
Train	9:35am	Amtrak Station	13h 48m	10:23pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	6:26am	Amtrak Station	13h 41m	7:07pm	Gateway Station	CheapestFastest

Last refresh of the prices: Last Saturday at 6:04 PM EST.

Compare 2 ways to go from Detroit to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 13 hours 41 minutes and with fares starting at just $75, it presents an excellent value for a comfortable ride.

1train per day

13h 41mAverage Duration

455 milesDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$71 - $213	Average Duration15h 50m	CO₂ emissions 18kg CO₂e
Train	Average Price$75 - $474	Average Duration13h 41m	CO₂ emissions 67kg CO₂e

Train Companies

Amtrak

4/55,604 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5604 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $75

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Detroit, MI to St. Louis by train

How much does a train ticket from Detroit to St. Louis cost?
How long is the train trip from Detroit to St. Louis?
How many daily trains are there between Detroit and St. Louis?
Which train companies travel from Detroit to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

$175

11/23

$123

Today

$160

11/25

$173

11/26

$212

11/27

$94

11/28

$166

11/29

$456

The cheapest trip from Detroit, MI to St. Louis was searched and found on Nov 27, 2025 with a price of $94

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to St. Louis, as early as possible.

You can expect to pay from $94 to $692 for a train ticket from Detroit, MI to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-11-27.