Next departures for Florence to Boston on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
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Recommended
Price and booking link
Train
Florence Station
South Station (Train Terminal)
Cheapest
Train
Florence Station
Boston Route 128, MA
Fastest
Train
Florence Station
South Station (Train Terminal)
No tags
Train
Florence Station
South Station (Train Terminal)
No tags
Train
Florence Station
South Station (Train Terminal)
No tags
Last refresh of the prices: Yesterday at 6:52 PM EST.
Compare 2 ways to go from Florence to Boston
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Boston. The journey takes about 19 hours 32 minutes and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $138
Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by train
How much does a train ticket from Florence to Boston cost?
The average train ticket price from Florence to Boston is $292. The best way to find train tickets from Florence to Boston is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Florence to Boston?
A train trip between Florence and Boston is around 19h 32m, although the fastest train will take about 17h 32m. This is the time it takes to travel the 729 miles that separates the two cities.
How many daily trains are there between Florence and Boston?
The number of trains from Florence to Boston can differ depending on the day of the week. On average, there are 5. Some trains are direct while others have layovers. Simplify your train trip from Florence to Boston by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Florence to Boston?
When taking the train from Florence to Boston, you can travel comfortably and safely with Amtrak.
What are the best sights and things to do in Boston?
Once in Boston, you can explore the city. The top sights and things to do are Freedom Trail, Boston Public Library, New England Aquarium, Boston Bruins at TD Garden, Duck Tour.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$207
11/19
$229
Today
$229
11/21
$216
11/22
$420
11/23
$302
11/24
$302
11/25
$551
The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Nov 18, 2025 with a price of $207
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Boston, MA, US, as early as possible.
You can expect to pay from $207 to $1,573 for a train ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $216 which is on 2025-11-21.