Train tickets from Florence, SC, US to Boston, MA, US

Next train departures

Next departures for Florence to Boston on November 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Florence Station
South Station (Train Terminal)Cheapest
AmtrakTrain
Florence Station
Boston Route 128, MAFastest
AmtrakTrain
Florence Station
South Station (Train Terminal)No tags
AmtrakTrain
Florence Station
South Station (Train Terminal)No tags
AmtrakTrain
Florence Station
South Station (Train Terminal)No tags

Last refresh of the prices: Yesterday at 6:52 PM EST.

Compare 2 ways to go from Florence to Boston

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Boston. The journey takes about 19 hours 32 minutes and with fares starting at just $138, it presents an excellent value for a comfortable ride.

5train per day
19h 32mAverage Duration
733 milesDistance
108kgCO₂ emissions
Average Price$101 - $545Average Duration1d 2h
30kg CO₂e
Average Price$138 - $663Average Duration19h 32m
108kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/18
$207
11/19
$229
Today
$229
11/21
$216
11/22
$420
11/23
$302
11/24
$302
11/25
$551
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Nov 18, 2025 with a price of $207

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $207 to $1,573 for a train ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $216 which is on 2025-11-21.

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