Trains tickets from Florence (SC), US to Chicago

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TodayMay 13
from $358
TomorrowMay 14
ThuMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20

Upcoming Train Schedules

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 13 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 13 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 13 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 13 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from Florence to Chicago.

Bus
Average Price$170 - $264Average Duration1d 7h
27kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$372 - $479Average Duration1d 10h
100kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 7 hours 11 minutes and with fares starting at just $170, it presents an excellent value for a comfortable ride.

6bus per day
1d 7hAverage Duration
$170Cheapest ticket
27kgCO₂ emissions

Train Florence to Chicago: Trip Overview

Please note, this information is subject to change.

Average ticket price$372
Average train trip duration1d 10h
Number of daily trains2
Earliest train departure11:32pm
Distance681 miles (1097 km)

Florence to Chicago Train

Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Florence to Chicago.

We make sure you can find a train service from Florence to Chicago from the most reliable train companies operating this trip.

From train tickets to high-end trains trip from Florence to Chicago, we offer a wide range of train services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Florence - Chicago

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/11
No data
05/12
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Today
$358
05/14
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05/15
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05/16
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05/17
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05/18
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busbud logoThe cheapest trip from Florence to Chicago was searched and found on May 13, 2025 with a price of $358

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence to Chicago, as early as possible.

About Train Travel

Train Travel Tips

Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Florence and Chicago is also a great way to travel to arrive in the city centre and save more time for your stay in Chicago.

Regional train? High-speed train? Whichever train to Chicago you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

The train emits up to 30x less CO2 for a trip between Florence and Chicago compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Florence to Chicago.

Did you know?

The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

Will you be returning to Florence by train?

Train from Chicago to Florence

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