Next departures for Florence to Pittsburgh on November 18
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Train
Florence Station
Union Station
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Train
Florence Station
Union Station
No tags
Train
Florence Station
Union Station
No tags
Train
Florence Station
Union Station
No tags
Train
Florence Station
Union Station
No tags
Compare 2 ways to go from Florence to Pittsburgh
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 17 hours 45 minutes and with fares starting at just $86, it presents an excellent value for a comfortable ride.
Based on 5593 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $199
Frequently asked questions about traveling from Florence, SC, US to Pittsburgh by train
How much does a train ticket from Florence to Pittsburgh cost?
The average train ticket price from Florence to Pittsburgh is $251. The best way to find train tickets from Florence to Pittsburgh is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Florence to Pittsburgh?
A train trip between Florence and Pittsburgh is around 1d , although the fastest train will take about 20h 33m. This is the time it takes to travel the 431 miles that separates the two cities.
How many daily trains are there between Florence and Pittsburgh?
The number of trains from Florence to Pittsburgh can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Florence to Pittsburgh by comparing and selecting the train that fits you travel style and budget on Busbud.
Which train companies travel from Florence to Pittsburgh?
When taking the train from Florence to Pittsburgh, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
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11/17
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Today
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11/19
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11/20
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11/21
$297
11/22
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11/23
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The cheapest trip from Florence, SC, US to Pittsburgh was searched and found on Nov 21, 2025 with a price of $297
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Pittsburgh, as early as possible.
You can expect to pay from $297 to $846 for a train ticket from Florence, SC, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $297 which is on 2025-11-21.