Bus Tickets from Florence, SC, US to Pittsburgh

Previously seen trips

Next departures for Florence to Pittsburgh on October 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Bus station
Pittsburgh Intermodal StationNo tags
Greyhound + FlixBus
Florence, SC
Pittsburgh Intermodal StationNo tags
Greyhound
Bus station
Pittsburgh Intermodal StationNo tags
Greyhound
Bus station
Pittsburgh Intermodal StationNo tags
Greyhound + FlixBus
Florence, SC
Pittsburgh Intermodal StationNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Pittsburgh.

Bus
Average Price$65 - $169Average Duration20h 30m
17kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$157 - $284Average Duration20h 33m
63kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Pittsburgh

Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 20 hours 30 minutes and with fares starting at just $65, it presents an excellent value for a comfortable ride.

1bus per day
20h 30mAverage Duration
$65Cheapest ticket
17kgCO₂ emissions

Bus Florence, SC, US to Pittsburgh: Trip Overview

Average ticket price$89
Average bus trip duration20h 30m
Number of daily buses1
Earliest bus departure12:05am
Distance432 miles (696 km)
Latest bus departure4:15pm

Florence to Pittsburgh Bus

Busbud helps you find a bus from Florence to Pittsburgh. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Florence to Pittsburgh will be provided by the most trusted bus companies.

Discover how much the bus trip from Florence to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Florence, SC, US - Pittsburgh

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/03
No data
10/04
$156
Today
$154
10/06
No data
10/07
No data
10/08
No data
10/09
No data
10/10
No data
busbud logoThe cheapest trip from Florence, SC, US to Pittsburgh was searched and found on Oct 5, 2025 with a price of $154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Pittsburgh, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Pittsburgh!

Much more than a mere vehicle taking you from Florence to Pittsburgh, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Florence to Pittsburgh will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Florence to Pittsburgh, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Florence, SC, US to Pittsburgh?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Pittsburgh to Florence, SC, US

You can also go to Pittsburgh by train

Train from Florence, SC, US to Pittsburgh

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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