Trains tickets from Harrisburg to Greenville, SC

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Compare 2 ways to go from Harrisburg to Greenville.

Bus
Average Price$83 - $322Average Duration20h 20m
19kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$187 - $381Average Duration16h 19m
70kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Harrisburg to Greenville

Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just $187, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage Duration
$187Cheapest ticket
70kgCO₂ emissions

Train Harrisburg to Greenville, SC: Trip Overview

Please note, this information is subject to change.

Average ticket price$276
Average train trip duration16h 19m
Number of daily trains1
Earliest train departure11:20am
Distance480 miles (774 km)
Latest train departure1:05pm

Harrisburg to Greenville Train

Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Harrisburg to Greenville.

We make sure you can find a train service from Harrisburg to Greenville from the most reliable train companies operating this trip.

Discover how much the train trip from Harrisburg to Greenville will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Harrisburg - Greenville, SC

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/26
$250
07/27
No data
Today
No data
07/29
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07/30
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07/31
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08/01
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busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on Jul 26, 2025 with a price of $250

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Greenville, SC, as early as possible.

About Train Travel

Train Travel Tips

Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Harrisburg and Greenville is also a great way to travel to arrive in the city centre and save more time for your stay in Greenville.

Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

With up to 30x less CO2 emissions for your train journey between Harrisburg and Greenville, the train is an ecological alternative to flights or personal cars.

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Harrisburg to Greenville.

Did you know?

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.

Will you be returning to Harrisburg by train?

Train from Greenville, SC to Harrisburg

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