Train from Harrisburg to Greenville, SC: Tickets & Schedules

Previously seen trips

Next departures for Harrisburg to Greenville on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags

Compare 2 ways to go from Harrisburg to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just $165, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage Duration
480 milesDistance
70kgCO₂ emissions
Average Price$70 - $371Average Duration22h 45m
19kg CO₂e
Average Price$165 - $677Average Duration16h 19m
70kg CO₂e

Frequently asked questions about traveling from Harrisburg to Greenville, SC by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/24
No data
11/25
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Today
$652
11/27
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11/28
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11/29
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11/30
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12/01
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busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on Nov 26, 2025 with a price of $652

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Greenville, SC, as early as possible.

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