Compare 2 ways to go from Milwaukee to Charleston.
Busbud recommends taking the bus from Milwaukee to CharlestonAmong the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 1 day, 18 hours 5 minutes and with fares starting at just $164, it presents an excellent value for a comfortable ride.
Train Milwaukee to Charleston, SC, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5432 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $272
Milwaukee to Charleston Train
Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Milwaukee to Charleston.
Train service from Milwaukee to Charleston will be provided by the most trusted companies.
Discover how much the train trip from Milwaukee to Charleston will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions for your trip Milwaukee - Charleston, SC, US
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milwaukee to Charleston, SC, US was searched and found on Aug 28, 2025 with a price of $274To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Milwaukee to Charleston, SC, US, as early as possible.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Milwaukee and Charleston is also a great way to travel to arrive in the city centre and save more time for your stay in Charleston.
No matter if you plan to take a regional or high-speed train to Charleston, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
With up to 30x less CO2 emissions for your train journey between Milwaukee and Charleston, the train is an ecological alternative to flights or personal cars.
Make a music playlist for your train ride from Milwaukee to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
Top Traveled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Trains Connecting Milwaukee
Trains Leaving from Milwaukee
Popular Trains Connecting Charleston
Trains Going to Charleston
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Columbia to New York City
- Train from Detroit to Red Wing
- Train from Holland to Taylor
- Train from Los Angeles to Glendale
- Train from Waterloo to Buffalo
- Train from Washington to Leavenworth
- Train from Niagara Falls to Ontario
- Train from Washington to Everett
- Train from Buffalo to New York City
- Train from Seattle to Washington
- Train from Rochester to New York City
- Train from Ventura to Simi Valley
- Train from Fayetteville to Cumberland
- Train from Newark to Essex