Next departures for Syracuse to Florence on November 18
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Train
Amtrak Station
Florence Station
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Train
Amtrak Station
Florence Station
No tags
Train
Amtrak Station
Florence Station
No tags
Train
Amtrak Station
Florence Station
No tags
Train
Amtrak Station
Florence Station
No tags
Compare 2 ways to go from Syracuse to Florence
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 20 hours 45 minutes and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Based on 5593 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $219
Frequently asked questions about traveling from Syracuse, US to Florence, SC, US by train
How much does a train ticket from Syracuse to Florence cost?
The average train ticket price from Syracuse to Florence is $246. The best way to find train tickets from Syracuse to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Syracuse to Florence?
A train trip between Syracuse and Florence is around 20h 4m, although the fastest train will take about 20h 4m. This is the time it takes to travel the 639 miles that separates the two cities.
How many daily trains are there between Syracuse and Florence?
The number of trains from Syracuse to Florence can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Syracuse to Florence by comparing and selecting the train that fits you travel style and budget on Busbud.
Which train companies travel from Syracuse to Florence?
When taking the train from Syracuse to Florence, you can travel comfortably and safely with Amtrak.
What are the best sights and things to do in Florence?
Once in Florence, you can explore the city. The top sights and things to do are Basilica Santa Croce, Basilica di San Lorenzo, Museo degli Innocenti, Palazzo Vecchio, Leonardo Da Vinci Museum.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$607
11/17
No data
Today
No data
11/19
$226
11/20
No data
11/21
No data
11/22
No data
11/23
No data
The cheapest trip from Syracuse, US to Florence, SC, US was searched and found on Nov 19, 2025 with a price of $226
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Florence, SC, US, as early as possible.
You can expect to pay from $226 to $695 for a train ticket from Syracuse, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $226 which is on 2025-11-19.